4/2011
vol. 92
abstract:
REVIEW PAPER Human cytomegalovirus infection
as a lifelong health problem
Agnieszka Modlińska-Cwalińska
,
Katarzyna Jończyk-Potoczna
,
BioTechnologia vol. 92(4) C pp. 352-357 C 2011
Online publish date: 2014/10/28
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Infections with human cytomegalovirus (HCMV) are widely spread worldwide. A clinical picture of the infection
varies and depends on the age of the patient and the condition of the immune system. Rapid dissemination
of HCMV is related to the presence of the virus in the peripheral blood cells. The most severe course of the disease
is observed in patients with congenital cytomegaly, organ transplant recipients and patients with either acquired
or inborn immune deficiencies. Chronic HCMV infection may lead to atherosclerosis and as a consequence,
to cardiovascular diseases such as: myocardial ischemia or infarction and hypertension. In addition, the relation
between HCMV infection and neoplastic transformation was noticed. Since diagnostic and therapeutic methods
are still imperfect, a development of an effective vaccine seems to be of key importance for a significant reduction
of the consequences of HCMV infection.
keywords:
HCMV, children, health problems
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