Radiation recall dermatitis induced by Amol during tamoxifen therapy – case report

Aleksander Obtułowicz; Magdalena Pirowska; Agnieszka Kosiniak-Kamysz

doi:10.5114/wo.2011.23008

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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3/2011
vol. 15

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abstract:

Case report

Radiation recall dermatitis induced by Amol during tamoxifen therapy – case report

Aleksander Obtułowicz

,

Magdalena Pirowska

,

Agnieszka Kosiniak-Kamysz

Współcz Onkol 2011; 15 (3): 168–171

DOI: https://doi.org/10.5114/wo.2011.23008

Online publish date: 2011/07/04

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In the course of radiation therapy different types of adverse reactions of the skin are observed in approximately 95% of patients. Among the various complications encountered after radiotherapy, radiation recall dermatitis (RRD) deserves special attention. Radiation dermatitis is a form of delayed hypersensitivity of irradiated skin, and the direct trigger factors are medicines – most chemotherapeutics. The reaction is an inflammatory dermatosis. It is limited to previously irradiated skin and appears a number of months after radiotherapy. The aetiology of RRD is still unclear. Its clinical presentation may vary from mild erythema to necrosis and ulceration. The article presents the case of a 50-year-old patient, who after radiotherapy for breast cancer, during the hormonal therapy (tamoxifen), developed RRD type skin reactions after skin application of Amol. The article presents a detailed differential diagnosis of skin changes of RRD type, and discusses the principles of treatment and prevention.

keywords:

Radiation recall dermatitis induced by Amol during tamoxifen therapy – case report

Aleksander Obtułowicz , Magdalena Pirowska , Agnieszka Kosiniak-Kamysz

radiation recall dermatitis, tamoxifen, Amol, breast cancer

Aleksander Obtułowicz

,

Magdalena Pirowska

,

Agnieszka Kosiniak-Kamysz