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Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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Original paper

Regulation of involucrin and signalling pathway in scleroderma epidermal keratinocytes

Jia-Qi Chen
1
,
Min Zheng
1
,
Wei Li
1
,
Jiong Zhou
1
,
Xiao-Yong Man
1

  1. Department of Dermatology, Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China
Adv Dermatol Allergol
DOI: https://doi.org/10.5114/ada.2024.144841
Online publish date: 2024/11/08
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1. Denton C, Khanna D. Systemic sclerosis. Lancet 2017; 390: 1685-99.
2. Asano Y, Takahashi T, Saigusa R. Systemic sclerosis: is the epithelium a missing piece of the pathogenic puzzle? J Dermatol Sci 2019; 94: 259-65.
3. Mccoy SS, Reed TJ, Berthier CC, et al. Scleroderma keratinocytes promote fibroblast activation independent of transforming growth factor beta. Rheumatology (Oxford) 2017; 56: 1970-81.
4. Aden N, Shiwen X, Aden D, et al. Proteomic analysis of scleroderma lesional skin reveals activated wound healing phenotype of the epidermal cell layer. Rheumatology (Oxford) 2008; 47: 1754-60.
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9. Man XY, Yang XH, Cai SQ, et al. Overexpression of vascular endothelial growth factor (VEGF) receptors on keratinocytes in psoriasis: regulated by calcium-independent of VEGF. J Cell Mol Med 2008; 12: 649-60.
10. Man XY, Yang XH, Cai SQ, et al. Immunolocalization and expression of vascular endothelial growth factor receptors (VEGFRs) and neuropilins (NRPs) on keratinocytes in human epidermis. Mol Med 2006; 12: 127-36.
11. Watt FM. Involucrin and other markers of keratinocyte terminal differentiation. J Invest Dermatol 1983; 81: 100s-3s.
12. Kim BE, Howell MD, Guttman E, et al. TNF-alpha downregulates filaggrin and loricrin through c-Jun N-terminal kinase: role for TNF-alpha antagonists to improve skin barrier. J Invest Dermatol 2011; 131: 1272-9.
13. Pascal LE, True LD, Campbell DS, et al. Correlation of mRNA and protein levels: cell type-specific gene expression of cluster designation antigens in the prostate. BMC Genom 2008; 9: 246.
14. Nie L, Wu G, Zhang W. Correlation between mRNA and protein abundance in Desulfovibrio vulgaris: a multiple regression to identify sources of variations. Biochem Biophys Res Commun 2006; 339: 603-10.
15. Mcmullan R, Lax S, Robertson VH, et al. Keratinocyte differentiation is regulated by the Rho and ROCK signaling pathway. Curr Biol 2003; 13: 2185-9.
Copyright: © 2024 Termedia Sp. z o. o. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license.
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