Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man

Artur Kowalik; Andrzej Wincewicz; Krzysztof Ossoliński; Sebastian Zięba; Janusz Kopczyński; Tadeusz Ossoliński; Stanisław Góźdź; Mariusz Koda; Stanisław Sulkowski

doi:10.5114/pjp.2020.99785

eISSN: 2084-9869
ISSN: 1233-9687

Polish Journal of Pathology

Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

3/2020
vol. 71

Send email

Copy url:

abstract:

Review paper

Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man

Artur Kowalik

^{1, 2, 3}

,

Andrzej Wincewicz

⁴

,

Krzysztof Ossoliński

⁵

,

Sebastian Zięba

¹

,

Janusz Kopczyński

⁶

,

Tadeusz Ossoliński

⁵

,

Stanisław S. Góźdź

^{7, 8}

,

Mariusz Koda

⁹

,

Stanisław T. Sulkowski

⁹

Department of Molecular Diagnostics, Holy Cross Oncology Centre, Kielce, Poland
Division of Medical Biology, Institute of Biology, Jan Kochanowski University, Kielce, Poland
Department of Tumour Pathology, National Research Institute of Oncology, Krakow Branch, Krakow, Poland
Specialist Medical Practice – Pathologist, Kielce, Poland
Department of Urology, John Paul II Hospital, Independent Public Health Care Unit in Kolbuszowa, Poland
Department of Pathology, Holy Cross Oncology Centre, Kielce, Poland
Department of Clinical Oncology, Jan Kochanowski University, Holy Cross Oncology Centre, Kielce, Poland
Department of Prophylaxis and Cancer Epidemiology, Collegium Medicum, Jan Kochanowski University, Kielce, Poland
Department of General Pathomorphology, Collegium Pathologicum, Medical University of Bialystok, Bialystok, Poland

Pol J Pathol 2020; 71 (3): 195-199

DOI: https://doi.org/10.5114/pjp.2020.99785

Online publish date: 2020/10/25

View full text Get citation

EndNote

Papers, Reference Manager, RefWorks, Zotero

AMA

Kowalik A, Wincewicz A, Ossoliński K, et al. Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man. Polish Journal of Pathology. 2020;71(3):195-199. doi:10.5114/pjp.2020.99785.

APA

Kowalik, A., Wincewicz, A., Ossoliński, K., Zięba, S., Kopczyński, J.,  & Ossoliński, T. et al. (2020). Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man. Polish Journal of Pathology, 71(3), 195-199. https://doi.org/10.5114/pjp.2020.99785

Chicago

Kowalik, Artur, Andrzej Wincewicz, Krzysztof Ossoliński, Sebastian Zięba, Janusz Kopczyński, Tadeusz Ossoliński,  and Stanisław S Góźdź et al. 2020. "Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man". Polish Journal of Pathology 71 (3): 195-199. doi:10.5114/pjp.2020.99785.

Harvard

Kowalik, A., Wincewicz, A., Ossoliński, K., Zięba, S., Kopczyński, J., Ossoliński, T., Góźdź, S., Koda, M.,  and Sulkowski, S. (2020). Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man. Polish Journal of Pathology, 71(3), pp.195-199. https://doi.org/10.5114/pjp.2020.99785

MLA

Kowalik, Artur et al. "Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man." Polish Journal of Pathology, vol. 71, no. 3, 2020, pp. 195-199. doi:10.5114/pjp.2020.99785.

Vancouver

Kowalik A, Wincewicz A, Ossoliński K, Zięba S, Kopczyński J, Ossoliński T et al. Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man. Polish Journal of Pathology. 2020;71(3):195-199. doi:10.5114/pjp.2020.99785.

PlumX metrics:

Here we review the role of GDNF, PTCH1, RNF213 illustrated by a case of renal cell carcinoma, chromophobe type (pT2a 8th pTNM edition) of the left kidney of 71-year-old man. Status of potential hotspots in 409 tumor genes were studied by means of next generation sequencing (NGS) technology (IonTorrent –

Thermo Fisher Scientific, USA) using Ion AmpliSeq™ Comprehensive Cancer Panel. Next-generation sequencing (NGS) revealed mutations of GDNF (NM_001190468: c. 328C>T, p.R110W, allelic frequency 46%), PTCH1 (NM_001083607:c. 2969C

keywords:

Review on significance of GDNF, PTCH1 and RNF213 in chromophobe renal cell carcinoma illustrated by the case of 71-years-old man

Artur Kowalik 1, 2, 3 , Andrzej Wincewicz 4 , Krzysztof Ossoliński 5 , Sebastian Zięba 1 , Janusz Kopczyński 6 , Tadeusz Ossoliński 5 , Stanisław S. Góźdź 7, 8 , Mariusz Koda 9 , Stanisław T. Sulkowski 9

GDNF, PTCH1, RNF213, chromophobe renal cell carcinoma

Artur Kowalik

^{1, 2, 3}

,

Andrzej Wincewicz

⁴

,

Krzysztof Ossoliński

⁵

,

Sebastian Zięba

¹

,

Janusz Kopczyński

⁶

,

Tadeusz Ossoliński

⁵

,

Stanisław S. Góźdź

^{7, 8}

,

Mariusz Koda

⁹

,

Stanisław T. Sulkowski

⁹