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eISSN: 2084-9877
ISSN: 1896-9666
Przegląd Kardiodiabetologiczny/Cardio-Diabetological Review
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1/2009
vol. 4
 
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abstract:

Review paper
Adiponectin, and the adiponectin paradox in human metabolism

Maciej Owecki

Przegląd Kardiodiabetologiczny 2009; 4, 1: 42–48
Online publish date: 2009/04/08
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Adiponectin, also referred to as Acrp30, AdipoQ, apM1, and GBP28, is a 276-amino acid protein specific for adipose tissue. This paper describes molecular mechanisms of adiponectin action, and clinical consequences of its various biochemical functions. Also, a common concept of the role of a low adiponectin level in the development of obesity, type 2 diabetes, insulin resistance, and dyslipidaemia is presented, and compared to other opinions that consider the paradoxical association between hypoadiponectinaemia and increased amount of fat tissue.
keywords:

adiponectin, adipocytokines, metabolism

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