Review paper<br>DNA and RNA oligonucleotides as a new class of drugs

Dorota Radomska-Leśniewska; Agata Hevelke; Ewa Jankowska-Steifer; Jacek Malejczyk

eISSN: 1644-4124
ISSN: 1426-3912

Central European Journal of Immunology

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

4/2009
vol. 34

Send email

Copy url:

abstract:

Review paper
DNA and RNA oligonucleotides as a new class of drugs

Dorota Radomska-Leśniewska

,

Agata Hevelke

,

Ewa Jankowska-Steifer

,

Jacek Malejczyk

Centr Eur J Immunol 2009; 34 (4): 280-283

Online publish date: 2009/12/30

View full text Get citation

Aptamers are short synthetic single-stranded DNA or RNA oligonucleotides forming unique 3-D conformation. They are able to bind and neutralize their target molecules with high specificity and affinity. Therefore, they may specifically interfere in vivo with some protein function and thus display drug-like properties. This paper provides a brief description of possible clinical application of aptamers arguing for their tremendous therapeutic possibilities.

keywords:

Review paperDNA and RNA oligonucleotides as a new class of drugs

Dorota Radomska-Leśniewska , Agata Hevelke , Ewa Jankowska-Steifer , Jacek Malejczyk

aptamer, DNA, RNA, cancer therapy, ocular diseases, viral diseases, circulations disorders

Review paper
DNA and RNA oligonucleotides as a new class of drugs

Dorota Radomska-Leśniewska

,

Agata Hevelke

,

Ewa Jankowska-Steifer

,

Jacek Malejczyk