eISSN: 2084-9869
ISSN: 1233-9687
Polish Journal of Pathology
Current issue Archive Manuscripts accepted About the journal Supplements Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

without publication fees
3/2014
vol. 65
 
Share:
Send email
Share:
abstract:

Review paper
Significance of selected antioxidant enzymes in cancer cell progression

Rafał Jakub Bułdak
,
Łukasz Bułdak
,
Michał Kukla
,
Andrzej Gabriel
,
Krystyna Żwirska-Korczala

Pol J Pathol 2014; 65 (3): 167-175
DOI: https://doi.org/10.5114/pjp.2014.45779
Online publish date: 2014/10/18
View full text Get citation
 
PlumX metrics:
Antioxidant enzymes (AOEs), including superoxide dismutase isoenzymes (SOD), catalase (CAT), glutathione peroxidase (GSH-Px) along with glutathione reductase (GR), reduced glutathione (GSH) and glutathione transferase (GST), are thought to be necessary for life processes in all oxygen-metabolizing cells by removing reactive oxygen species (ROS). The biological significance of AOEs in transformed cells is still unclear, but their capacity to survive may be affected by changes in cellular processes such as proliferation, invasiveness, migration, apoptosis and drug resistance. This review summarizes the significance of antioxidant enzymes in cancer cell progression mainly in an in vitro context.
keywords:

antioxidant enzymes, reactive oxygen species, cancer progression, lipid peroxidation, ROS-mediated treatment of cancer
Termedia
About us Contact
Copyright notice Privacy policy Advertising policy Contact us
Quick links
Journals Books eBooks Events
© 2024 Termedia Sp. z o.o.
Developed by Bentus.