eISSN: 2299-0046
ISSN: 1642-395X
Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii
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SCImago Journal & Country Rank
6/2011
vol. 28
 
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abstract:

Review paper
Selectins in dermatology

Wiesława Sudnik
,
Aleksandra Dańczak-Pazdrowska
,
Wojciech Silny
,
Dorota Jenerowicz

Post Dermatol Alergol 2011; XXVIII, 6: 514–521
Online publish date: 2011/12/28
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In the course of an inflammatory reaction an inflow of cells takes place to the site of inflammation. At the beginning of the process the main role is played by selectins, the group of three proteins responsible for initiation of leukocyte adhesion to endothelial cells. Selectins are present on the cell surface while serum and body fluids contain their soluble forms. In the course of several inflammatory diseases alterations in intensity of E-selectin expression or in concentration of their soluble forms were detected. We have devoted our attention to the problem of selectins in dermatology.
keywords:

selectins, ligands, selectins in dermatology

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