Rhabdomyosarcoma of the head and neck in children

Joanna Radzikowska; Wojciech Kukwa; Andrzej Kukwa; Anna Czarnecka; Antoni Krzeski

doi:10.5114/wo.2015.49158

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

Current issue Archive Manuscripts accepted About the journal Supplements Addendum Special Issues Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

2/2015
vol. 19

Send email

Copy url:

abstract:

Review paper

Rhabdomyosarcoma of the head and neck in children

Joanna Radzikowska

,

Wojciech Kukwa

,

Andrzej Kukwa

,

Anna Czarnecka

,

Antoni Krzeski

Contemp Oncol (Pozn) 2015; 19 (2): 98–107

DOI: https://doi.org/10.5114/wo.2015.49158

Online publish date: 2015/02/13

View full text Get citation

PlumX metrics:

Rhabdomyosarcoma (RMS) is the most frequent soft tissue sarcoma in children. It is localized in the head and neck region in 40% of cases. Treatment of RMS is complex, including multi-drug chemotherapy, radiotherapy and surgery. The progress that has been accomplished in oncology in recent decades significantly improved outcomes. The 5-year survival rate raised from 25% in 1970 to 73% in 2001, according to IRS-IV data. The outcome is influenced by primary tumor localization, clinical staging, histological tumor type and age at the moment of diagnosis. The relatively rare incidence of these tumors resulted in difficulties in creating more standardized therapeutic protocols. Comparison of outcomes in large patients groups led to an increase in the number of patients with complete remission. Although survival rates of RMS patients have improved, searching for new therapeutic modalities and substances is still essential to improve outcomes in cases of more advanced stages and unfavorable tumor localizations.

keywords:

Rhabdomyosarcoma of the head and neck in children

Joanna Radzikowska , Wojciech Kukwa , Andrzej Kukwa , Anna Czarnecka , Antoni Krzeski

head and neck rhabdomyosarcoma, sarcoma, surgery, radiation therapy, chemotherapy

Joanna Radzikowska

,

Wojciech Kukwa

,

Andrzej Kukwa

,

Anna Czarnecka

,

Antoni Krzeski