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5/2015
vol. 68 abstract:
Sclerosing Rhabdomyosarcoma of the buccal mucosa: a cautionary tale
Eugene Omakobia
1
,
Natasha Berridge
1
,
Colin Liew
2
,
Simon Morley
2
Online publish date: 2015/12/24
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Rhabdomyosarcoma (RMS) is a malignant soft tissue tumour of skeletal muscle origin with a predilection for head and neck sites, including the oral cavity. Whilst RMS is the commonest soft tissue sarcoma in children, it is rare in adults, accounting for <1% of all malignancies. Three main histologic subtypes of RMS are recognised; namely embryonal, alveolar and pleiomorphic. There appears to be a newly emerging sclerosing variant which does not fit into the current classification. Here, we report an additional case of sclerosing RMS of the buccal mucosa in a 21 year old female. We place particular emphasis on the difficulties in diagnosis of RMS affecting the oral cavity; since many cases are initially misdiagnosed as infection of dental origin. This case not only serves as a useful reminder to clinicians not to forget this important diagnosis, but also contributes to the growing body of evidence supporting a new sclerosing variant of RMS.
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