Selected novel aspects in pathogenesis of lupus erythematosus – interdisciplinary view

Agnieszka Kalińska-Bienias; Bartosz Foroncewicz; Piotr Bienias; Cezary Kowalewski

doi:10.5114/dr.2016.62884

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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5/2016
vol. 103

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abstract:

Special paper

Selected novel aspects in pathogenesis of lupus erythematosus – interdisciplinary view

Agnieszka Kalińska-Bienias

,

Bartosz Foroncewicz

,

Piotr Bienias

,

Cezary Kowalewski

Przegl Dermatol 2016, 103, 345–353

DOI: https://doi.org/10.5114/dr.2016.62884

Online publish date: 2016/10/20

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Lupus erythematosus is an autoimmune disease characterized by complex immune disturbances concerning humoral and cell-mediated immune responses. Despite intensive research, many pathological processes regarding this disorder remain unexplained. During interdisciplinary investigations on the etiology of lupus and its complications special interest has recently been referred to heat-shock proteins, antibodies directed against such proteins and galectin-3. These issues are extensively studied not only by dermatologists and rheumatologists, but also by cardiologists (in terms of cardiovascular complications) and nephrologists (in terms of lupus nephritis). This study presents the current state of dermatological, nephrological and cardiological knowledge on this topic.

keywords:

Selected novel aspects in pathogenesis of lupus erythematosus – interdisciplinary view

Agnieszka Kalińska-Bienias , Bartosz Foroncewicz , Piotr Bienias , Cezary Kowalewski

cutaneous lupus erythematosus, systemic lupus erythematosus, heat-shock proteins, galectin-3, pathogenesis

Agnieszka Kalińska-Bienias

,

Bartosz Foroncewicz

,

Piotr Bienias

,

Cezary Kowalewski