Significance of cytological and microbiological examination in prophylaxis of cervical carcinoma at girls

Objectives: cytological examination plays a essential role in prophilaxis of cervical carcinoma. Furthermore all of concomitant states linking with carcinogenesis in cervix, vagina and vulva must be display. Oncogenic types of human papilloma virus there are well-known carcinogens in uterine cervix. Sexual activity from earliest youth, cervical erosion and sexual trannsmited diseases especially Chlamydia trachomatis there are predisposing factors.
Materials and methods: Material consist of 21563 patients 11-19 years old. Twenty thousands examinations were executed at high school pupils and 102 examinations were taken from high risk group of vaginitis and cervical carcinoma (girls from Reformatory House). Investigations were made according to Papanicolau test, besides group II PAP with inflammatory reaction was separated. Furthermore at 102 girls from Reformatory House bacteriological examination of vaginal smears, identification of HPV type (PCR method) and Chlamydia trachomatis (EIA method) were executed. 1461 cytological examinations were done according to Bethesda method.
Results: At high risk group 86 % girls have had II group with inflammatory reaction and 11% III group according to Papanicolau. Moreover in this group were 25% cases with HPV and 32% cases with Chlamydia trachomatis infections. Among girls examined according to Bethesta 46% cases of category BIIC were detected. At this group of patients also 7 cases of LSIL and HSIL were diagnosed. At four of them HPV infection were recognized.
Conclusions: All sexual active girls ought to be taken out with active prevention of cervical carcinoma. There is necessity of active prevention, education and cytological screening in this group of patients.