eISSN: 2084-9842
ISSN: 1643-9279
Postępy w chirurgii głowy i szyi/Advances in Head and Neck Surgery
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1/2022
vol. 21
 
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abstract:
Case report

Significant hearing improvement as a result of rituximab treatment in a patient with granulomatosis with polyangiitis – a case report

Maciej Krawczyk
1
,
Mikołaj Lewandowski
2
,
Krzysztof Piwowarczyk
3
,
Małgorzata Wierzbicka
1

  1. Klinika Otolaryngologii i Onkologii Laryngologicznej, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
  2. Szpital Kliniczny im. Heliodora Święcickiego Uniwersytetu Medycznego im. Karola Marcinkowskiego w Poznaniu
  3. Klinika Foniatrii i Audiologii, Uniwersytet Medyczny im. Karola Marcinkowskiego w Poznaniu
Postępy w Chirurgii Głowy i Szyi 2022; 1: 17–23
Online publish date: 2022/07/06
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Granulomatosis with polyangiitis is a rare disease, with small vessel vasculitis leading to progressive damage of vital organs. The mainstay of treatment is immunosupressive therapy. Exacerbations of the disease are prevalent and damages of tissues may result in organs failures. In our paper we present a case of a patient, who was qualified to biologic therapy with rituximab due to ongoing ear-nose-throat (ENT) symptoms worsening. Remission of rhinolaryngologic complaints was not met despite rituximab treatment, however significant improvement in hearing occurred.
keywords:

granulomatosis with polyangiitis, Wegener’s granulomatosis, hearing loss, rituximab
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