Signs and symptoms, evaluation, and management of genitourinary tract consequences of premature ovarian insufficiency

Anna Calik-Ksepka; Monika Grymowicz; Ewa Rudnicka; Jolanta Skórska; Paulina Machura; Wojciech Pięta; Roman Smolarczyk

doi:10.5114/pm.2018.78558

eISSN: 2299-0038
ISSN: 1643-8876

Menopause Review/Przegląd Menopauzalny

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3/2018
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abstract:

Review paper

Signs and symptoms, evaluation, and management of genitourinary tract consequences of premature ovarian insufficiency

Anna Calik-Ksepka

,

Monika Grymowicz

,

Ewa Rudnicka

,

Jolanta Skórska

,

Paulina Machura

,

Wojciech Pięta

,

Roman Smolarczyk

Menopause Rev 2018; 17(3): 131-134

DOI: https://doi.org/10.5114/pm.2018.78558

Online publish date: 2018/09/30

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Premature ovarian insufficiency (POI) occurs in 1% of women under 40 years old. Hypoestrogenism associated with this condition may result in vaginal atrophy and urine incontinence, called genitourinary syndrome. The symptoms include: vaginal dryness, irritation, dyspareunia, and dysuria. There is relative lack of studies on the occurrence and treatment of genitourinary problems in women with POI. Prevalence rates vary from 17 to 54% depending on cause, duration of oestrogen depletion, and the treatment used. Patients with POI gain lower scores in tests measuring vaginal health or sexual function in comparison to healthy peers. Hormonal treatment in premature ovarian insufficiency is recommended until the natural age of menopause. The vaginal route of oestrogen administration is supposed to be the criterion standard in treating genitourinary symptoms. Androgen supplementation is not routinely recommended.

keywords:

Signs and symptoms, evaluation, and management of genitourinary tract consequences of premature ovarian insufficiency

Anna Calik-Ksepka , Monika Grymowicz , Ewa Rudnicka , Jolanta Skórska , Paulina Machura , Wojciech Pięta , Roman Smolarczyk

premature ovarian insufficiency, genitourinary syndrome, oestrogen therapy

Anna Calik-Ksepka

,

Monika Grymowicz

,

Ewa Rudnicka

,

Jolanta Skórska

,

Paulina Machura

,

Wojciech Pięta

,

Roman Smolarczyk