eISSN: 1897-4295
ISSN: 1734-9338
Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej
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3/2013
vol. 9
 
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Special papers
Midterm results of sildenafil therapy in two complex patients with elevated pulmonary artery pressure after cavopulmonary connection

Jacek Białkowski
,
Małgorzata Szkutnik
,
Roland Fiszer

Postep Kardiol Inter 2013; 9, 3 (33): 262–264
DOI: https://doi.org/10.5114/pwki.2013.37506
Online publish date: 2013/09/16
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Two cases are presented. In the first patient (8-year-old boy) after Glenn operation without closure of pulmonary outflow from the common ventricle (SV-PA) despite transcatheter SV-PA closure increased mean pulmonary artery pressure (mPAP) (22 mm Hg) remained. After 6 months of sildenafil therapy he was catheterized again. His mPAP dropped to 10 mm Hg and a Fontan operation was subsequently performed. The second patient was a 25-year-old man, 20 years after a Fontan operation, presenting protein losing enteropathy and severe heart failure. All syndromes diminished significantly after medical therapy with sildenafil. Good clinical results of sildenafil therapy were maintained after 1 and 4 years of treatment. Chronic therapy with sildenafil can be beneficial in patients before and after the Fontan operation with elevated pulmonary artery pressure.
keywords:

sildenafil, Fontan operation
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