Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review

Krystyna Romańska-Gocka; Jacek Gocki; Waldemar Placek; Barbara Zegarska; Paweł Krause

doi:10.5114/aoms.2010.13521

eISSN: 1896-9151
ISSN: 1734-1922

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abstract:

Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review

Krystyna Romańska-Gocka

,

Jacek Gocki

,

Waldemar Placek

,

Barbara Zegarska

,

Paweł Krause

Arch Med Sci 2010; 6, 1: 130-134

DOI: https://doi.org/10.5114/aoms.2010.13521

Online publish date: 2010/03/09

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We present a case of Stevens Johnson syndrome in a child after carbamazepine application and Stevens Johnson/TEN overlap syndrome in an adult after amoxicillin application. On the basis of two reported cases we review the most commonly associated drugs, the postulated pathogenesis, clinical manifestation and management in these severe life-threatening diseases. We especially discuss the controversial systemic corticosteroid therapy. Topical care is also discussed.

keywords:

Stevens Johnson syndrome after carbamazepine and SJS/TEN overlap syndrome after amoxicillin: case reports and a review

Krystyna Romańska-Gocka , Jacek Gocki , Waldemar Placek , Barbara Zegarska , Paweł Krause

Stevens Johnson syndrome

Krystyna Romańska-Gocka

,

Jacek Gocki

,

Waldemar Placek

,

Barbara Zegarska

,

Paweł Krause