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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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1/2020
vol. 107
 
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abstract:
Case report

Subcorneal pustular dermatosis successfully treated with acitretin

Andrzej K. Jaworek
1
,
Joanna A. Radzimowska-Dudek
1
,
Paweł Brzewski
1
,
Grzegorz Dyduch
2
,
Przemysław Hałubiec
3
,
Anna Wojas-Pelc
1

  1. Department of Dermatology, Jagiellonian University Medical College, Krakow, Poland/Katedra i Klinika Dermatologii, Collegium Medicum, Uniwersytet Jagielloński, Kraków, Polska
  2. Department of Pathomorphology, Jagiellonian University Medical College, Krakow, Poland/Katedra Patomorfologii, Collegium Medicum, Uniwersytet Jagielloński, Kraków, Polska
  3. SSG Dermatology, Jagiellonian University Medical College, Krakow, Poland/ SKN Dermatologii, Collegium Medicum, Uniwersytet Jagielloński, Kraków, Polska
Dermatol Rev/Przegl Dermatol 2020, 107, 52-62
DOI: https://doi.org/10.5114/dr.2020.93972
Online publish date: 2020/03/30
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Introduction
Subcorneal pustular dermatosis is a rare and chronic dermatosis which often has a recurrent course. The differential diagnosis of the condition should include above all pustular psoriasis and IgA pemphigus.

Objective
Presentation of a case of subcorneal pustular dermatosis successfully treated with acitretin.

Case report
A 28-year-old male patient was admitted to the Department with extensive erythematous eruptions arranged in a polycyclic pattern with small pustules on the periphery. The findings of histopathological examination confirmed the diagnosis of subcorneal pustular dermatosis. After introducing treatment with acitretin a remission of skin lesions was achieved.

Conclusions
The reported case and the literature data show that the differential diagnosis of subcorneal pustular dermatosis continues to be a clinical and histopathological challenge. Because of therapeutic differences associated with the disease entities in question, the establishment of correct diagnosis of subcorneal pustular dermatosis is especially important, while the improvement seen in the patient’s condition confirms the efficacy of acitretin in the treatment of the disease.

keywords:

subcorneal pustular dermatosis, Sneddon-Wilkinson syndrome, IgA pemphigus, pustular psoriasis
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