Systemic sclerosis – prognostic factors, disease activity and severity

Anna Lis-Święty; Ligia Brzezińska-Wcisło

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

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6/2010
vol. 97

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abstract:

Review paper

Systemic sclerosis – prognostic factors, disease activity and severity

Anna Lis-Święty

,

Ligia Brzezińska-Wcisło

Przegl Dermatol 2010, 97, 398–405

Online publish date: 2011/01/03

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Systemic sclerosis is a connective tissue disease characterized by heterogeneous clinical picture, course and prognosis. It is hard to evaluate severity of the disease in individual clinical cases. There are not distinct phases of disease flare and remission. Lesions resulting from the inflammatory process (active disease), and from fibrosis (irreversible damage), can occur. Introduction to clinical practice of new biomarkers could be helpful for determination of indications for intensive immunosuppressive treatment and evaluation of its efficacy.

keywords:

Systemic sclerosis – prognostic factors, disease activity and severity

Anna Lis-Święty , Ligia Brzezińska-Wcisło

systemic scleroderma, antinu­-clear antibody, biomarkers

Anna Lis-Święty

,

Ligia Brzezińska-Wcisło

systemic scleroderma, antinu-clear antibody, biomarkers