Current supplement Archive Acta Ophthalmologica Polonica |
1-2/2004
vol. 106 abstract:
Experimental research
The antibodies anty beta-2 glikoprotein I level in serum and aqueous humor in patients with glaucoma and their influence on the static perimetry
Małgorzata Latalska
1
,
Marek Gerkowicz
1
,
Ewa Kosior-Jarecka
2
,
Maria Kozioł-Montewka
2
,
Małgorzata Pietraś-Trzpiel
1
KLINIKA OCZNA 2004, Supl. 1-2: S160–S161
Online publish date: 2022/12/30
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Purpose
The evaluation of the relationships between the antibodies anty beta-2 glikoprotein I in serum and aqueous humor of the glaucoma patients to the visual field defects. Material and methods 48 persons (38 women and 17 men), aged 30-86 (mean age 70), suffering from glaucoma was examined. There were 19 with POAG, 18 with PACG and 11 with PEXG. All patients have undergone trabeculectomia. In plasma and anterior chamber fluid the level of antibodies to beta-2 glicoprotein I classes IgA and IgG were measured using ELISA method (commercial kits produced by Euroimmun), according to producer's instruction. The visual field defects were examined with Humphrey static perimetry. Statistical analysis was performed using Spearman test. Results There were no significant correlations between antibodies anty beta-2 glikoprotein I, static perimetry, age and duration of the disease. Conclusions There have not been stated any relationships between the static perimetry to antiphospholipid antibodies level in serum and aqueous humor in patients with glaucoma. It is the preliminary communication. keywords:
glaucoma, antibodies to beta-2 glikoprotein I, serum, aqueous humor, perimetry |