The diagnostics of colorectal cancer

Magdalena Świderska; Barbara Choromańska; Ewelina Dąbrowska; Emilia Konarzewska-Duchnowska; Katarzyna Choromańska; Grzegorz Szczurko; Piotr Myśliwiec; Jacek Dadan; Jerzy Robert Ładny; Krzysztof Zwierz

doi:10.5114/wo.2013.39995

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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1/2014
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abstract:

Review paper

The diagnostics of colorectal cancer

Magdalena Świderska

,

Barbara Choromańska

,

Ewelina Dąbrowska

,

Emilia Konarzewska-Duchnowska

,

Katarzyna Choromańska

,

Grzegorz Szczurko

,

Piotr Myśliwiec

,

Jacek Dadan

,

Jerzy Robert Ładny

,

Krzysztof Zwierz

Contemp Oncol (Pozn) 2014; 18 (1): 1–6

DOI: https://doi.org/10.5114/wo.2013.39995

Online publish date: 2013/12/20

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Colorectal cancer (CRC) is one of the most frequent human malignant neoplasms. CRC has an estimated incidence of more than 1,000,000 new cases annually worldwide. Approximately one out of three people who develop CRC dies from the disease. Furthermore, CRC often affects inhabitants of industrialized countries in comparison to less developed countries. Several markers of colon cancer, including CEA, CA-19-9, TPS, TAG-72 and lysosomal hydrolases, have been identified and are now being adopted in routine clinical practice. Increased values of these markers are often the first signal of recurrence or metastases, which is useful in prediction and prognosis of clinical outcome of patients with CRC. Determination of the activity of lysosomal exoglycosidases in body fluids may bring some hope of improving diagnosis of colorectal cancer. However, it has to be remembered that currently the most effective diagnostic method of CRC is endoscopy.

keywords:

The diagnostics of colorectal cancer

Magdalena Świderska , Barbara Choromańska , Ewelina Dąbrowska , Emilia Konarzewska-Duchnowska , Katarzyna Choromańska , Grzegorz Szczurko , Piotr Myśliwiec , Jacek Dadan , Jerzy Robert Ładny , Krzysztof Zwierz

colorectal cancer, tumor markers, endoscopy, lysosomal exoglycosidases

Magdalena Świderska

,

Barbara Choromańska

,

Ewelina Dąbrowska

,

Emilia Konarzewska-Duchnowska

,

Katarzyna Choromańska

,

Grzegorz Szczurko

,

Piotr Myśliwiec

,

Jacek Dadan

,

Jerzy Robert Ładny

,

Krzysztof Zwierz