The effect of <i>Aeromonas hydrophila</i> infection on the non-specific immunity of blunt snout bream (<i>Megalobrama amblycephala</i>)

Hu Xia; Ying Tang; Fenghui Lu; Yushuang Luo; Pinhong Yang; Wenbin Wang; Jigang Jiang; Na Li; Qing Han; Fei Liu; Lianggvo Liu

doi:10.5114/ceji.2017.70965

eISSN: 1644-4124
ISSN: 1426-3912

Central European Journal of Immunology

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3/2017
vol. 42

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abstract:

Experimental immunology

**The effect of Aeromonas hydrophila infection on the non-specific immunity of blunt snout bream (Megalobrama amblycephala)**

Hu Xia

,

Ying Tang

,

Fenghui Lu

,

Yushuang Luo

,

Pinhong Yang

,

Wenbin Wang

,

Jigang Jiang

,

Na Li

,

Qing Han

,

Fei Liu

,

Lianggvo Liu

(Centr Eur J Immunol 2017; 42 (3): 239-243)

DOI: https://doi.org/10.5114/ceji.2017.70965

Online publish date: 2017/10/30

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Aeromonas hydrophila is the main reason of epidemic septicaemia for freshwater fish. In the present study, the effect of Aeromonas hydrophila infection on the non-specific immunity of blunt snout bream (Megalobrama amblycephala) was studied. After Aeromonas hydrophila challenge, lysozyme activity was significantly increased at 4 h, 1 d, 3 d, 5 d, 14 d and 21 d. An increased level of lysozyme activity indicated a natural protective mechanism in fish. The significant increases of superoxide dismutase activity and catalase activity in treatment group were detected at 4 h, 1 d, 3 d, 5 d, 14 d and 21 d after Aeromonas hydrophila challenge. Increase in the superoxide anion and H₂O2 is considered to be beneficial for self-protection from disease. Acid phosphatase activity increased significantly at 1 d, 3 d and 5 d after Aeromonas hydrophila challenge. Alkaline phosphatase activity in treatment group showed significant increase at 4 h, 1 d, 3 d, 5 d, 14 d and 21 d compared to control group. Increased phosphatase activity indicates higher breakdown of the energy reserve, which is utilized for the growth and survival of fish. These results revealed that the non-specific immunity of fish played an important role in self-protection after pathogens infection.

keywords:

The effect of Aeromonas hydrophila infection on the non-specific immunity of blunt snout bream (Megalobrama amblycephala)

Hu Xia , Ying Tang , Fenghui Lu , Yushuang Luo , Pinhong Yang , Wenbin Wang , Jigang Jiang , Na Li , Qing Han , Fei Liu , Lianggvo Liu

Blunt snout bream (Megalobrama amblycephala), Aeromonas hydrophila, SOD, Catalase activity, lysozyme activity, non-specific immunity

**The effect of Aeromonas hydrophila infection on the non-specific immunity of blunt snout bream (Megalobrama amblycephala)**

Hu Xia

,

Ying Tang

,

Fenghui Lu

,

Yushuang Luo

,

Pinhong Yang

,

Wenbin Wang

,

Jigang Jiang

,

Na Li

,

Qing Han

,

Fei Liu

,

Lianggvo Liu