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1/2011
vol. 113 abstract:
Original paper
The effect of genetic factors on the occurrence of myopia
Damian Czepita
1
,
Artur Mojsa
1
,
Maria Ustianowska
1
,
Maciej Czepita
1
,
Ewelina Lachowicz
1
Klinika Oczna 2011, 113 (1): 22-24
Online publish date: 2011/04/17
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Introduction
The aim of this study was to investigate on a large population if and how genetic factors have an influence on the occurrence of myopia. Material and methods A total of 5533 students were examined (2659 boys and 2874 girls, in age 6−18 years, mean age 11.9, S.D. 3.2). The examination included retinoscopy under cycloplegia induced with 1% tropicamide. Myopia was defined as a spherical equivalent of at least -0.5 dioptres. The students and their parents completed a questionnaire on the child’s family history of myopia. Data analysis was performed using chi-squared test; p-values of <0.05 were considered statistically significant. Results It was found that myopia occurs more often in students whose father (p<0.001), mother (p<0.001) or siblings (p<0.0001) have myopia. A relation between the occurrence of myopia in grandparents and grandchildren was not observed (p>0.05). Conclusions The obtained results indicate that genetic factors have a significant effect on the occurrence of myopia. keywords:
genetic factors, myopia |
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POLSKI
