eISSN: 2449-8238
ISSN: 2392-1099
Clinical and Experimental Hepatology
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SCImago Journal & Country Rank
3/2022
vol. 8
 
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abstract:
Review paper

The effects of seaweed supplementation consumption for improvement of liver injury in patients with non-alcoholic fatty liver disease: a systematic review

Muhammad Luthfi Adnan
1
,
Miranti Dewi Pramaningtyas
1

  1. Department of Physiology, Faculty of Medicine, Universitas Islam Indonesia, Sleman, Special Region of Yogyakarta, Indonesia
Clin Exp HEPATOL 2022; 8, 3: 171-177
Online publish date: 2022/08/04
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Seaweed is a food that is widely consumed by Asian people and has many health benefits, including lipid and glycemic reduction, but the effect of seaweed on non-alcoholic fatty liver disease (NAFLD) has not been widely discussed. This study aims to compare the effect of seaweed consumption on improving liver injury in NAFLD patients. The primary outcome is the change of liver enzymes (alanine aminotransferase [ALT], aspartate aminotransferase [AST], alkaline phosphatase [ALP], and g-glutamyl transferase [GGT]), while the secondary outcome includes body weight, waist circumstance, body mass index (BMI), lipid profile, insulin level, and insulin sensitivity and any related metabolic indicators. There was significant liver improvement in the intervention group, but some parameters from secondary outcomes showed no significant effect. Further studies with larger and heterogeneous populations are still needed to confirm the effectiveness of seaweed supplementation in NAFLD patients.
keywords:

diet, fatty liver, liver enzymes, non-alcoholic fatty liver disease, seaweed

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