eISSN: 1897-4309
ISSN: 1428-2526
Contemporary Oncology/Współczesna Onkologia
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6/2005
vol. 9
 
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abstract:

The impact of erythropoietin treatment of anemia on the effectiveness of chemotherapy: analysis of selected parameters and clinical data

Marek Pawlicki
,
Jan Kulpa
,
Beata Żuchowska
,
Urszula Rychlik
,
Zofia Stasik

Współcz Onkol (2005); 9: 237-240
Online publish date: 2005/09/06
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Anemia is a frequent complication of cancer. It may be exclusively a consequence of the presence of malignant disease itself (cancer-related anemia; CRA) or a result of cancer treatment methods, radiotherapy and/or cytotoxic chemotherapy (radio- and chemotherapy-induced anemia). The aim of the presented study was to evaluate effectiveness of anemia treatment with erythropoietin. Pivotal groups of 68 patients were treated with erythropoietin due to cancer-related anemia occurring before or in the course of chemotherapy. The percentage of patients (52.4%) with an observed increase in the hemoglobin level (at least by 2 g/dl) was lower than data published in other studies. The treatment was well tolerated. Only in one case (1.47%) it was necessary to discontinue treatment because of deep vein thrombosis. The effectiveness of erythropoietin treatment seems to depend on the patients\' condition, pretreatment hemoglobin level (<8.5 g/dl) and duration of chemotherapy.
keywords:

anemia, erythropoietin, chemotherapy effectiveness

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