eISSN: 1644-4124
ISSN: 1426-3912
Central European Journal of Immunology
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3/2003
vol. 28
 
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abstract:

The in vivo effect of Echinacea purpurea succus on various functions of human blood leukocytes

Beata Białas-Chromiec
,
Beata Kapałka
,
Dorota Radomska-Leśniewska
,
Ewa Skopińska-Różewska
,
Ewa Sommer
,
Irena Sokolnicka
,
Małgorzata Filewska
,
Urszula Demkow

Centr Eur J Immunol 2003; 28 (3): 126–130
Online publish date: 2004/05/04
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17 healthy human volunteers were treated for 7 days with 6 ml of Echinacea purpurea succus daily (IMMUNAL drops, LEK Slovenia) or placebo. Blood from cubital vein was collected twice- before and after treatment. The following parameters were evaluated: (1) release of growth factors by mononuclear leukocytes (human leukocyte-induced angiogenesis, H LIA test); (2) in vitro mononuclear leukocytes response to mitogen PHA, (3H thymidine); (3) chemiluminescent activity of granulocytes, (4) CD4 and CD8 lymphocyte markers.
Echinacea administration resulted in stimulation of proliferative and angiogenic activity of blood mononuclear leukocytes, stimulation of blood granulocytes activity and increase of CD4/CD8 ratio.
keywords:

Echinacea purpurea, in vivo treatment, human volunteers, blood leukocytes
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