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2/2006
vol. 108 abstract:
Experimental research
The influence of dopamine injected into the lateral geniculate body on flash visual evoked response in rats
Agata R. Plech
1
,
Ewa Herba
1
,
Dorota Pojda-Wilczek
1
,
Katarzyna Makowiecka-Obidzińska
1
,
Stefan M. Pojda
1
,
Andrzej Plech
2
Online publish date: 2006/06/25
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Purpose
Numerous neurotransmitters and neuromodulators operating on all levels of the visual system, influence the parameters of cortical evoked response. The aim of this study was to find the influence of dopamine (DA) injected into the lateral geniculate body (nucleus) on flash visual evoked response (FVEP). Material and methods The experiments were performed on adult Wistar rats. They were implanted with 1 caniula conducted into the lateral geniculate body and 2 electrodes: active under the skull on dura mater in occipital region of brain and reference one on the skull in the interorbital region. FVEPs curve before and after injection into the lateral geniculate body 0.9% NaCl and DA were analyzed. Results DA in the lateral geniculate body causes increasing latency and amplitude of FVEP peaks. Conclusions Dopamine in the lateral geniculate body can improve visual perception in the occipital cortex. keywords:
visual evoked potentials, lateral geniculate body, dopamine, rats |
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POLSKI
