The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease

Sevilay Kılıç; Selda Işık; Meliha Merve Hiz; Dilek Ülker Çakır; Hakan Türkön; Sibel Cevizci; Zerrin Ogretmen

doi:10.5114/ada.2016.62840

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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5/2016
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abstract:

Original paper

The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease

Sevilay Kılıç

,

Selda Işık

,

Meliha Merve Hiz

,

Dilek Ülker Çakır

,

Hakan Türkön

,

Sibel Cevizci

,

Zerrin Ogretmen

Adv Dermatol Allergol 2016; XXXIII (5): 345-348

DOI: https://doi.org/10.5114/ada.2016.62840

Online publish date: 2016/10/21

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AMA

Kılıç S, Işık S, Hiz M, et al. The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2016;33(5):345-348. doi:10.5114/ada.2016.62840.

APA

Kılıç, S., Işık, S., Hiz, M., Çakır, D., Türkön, H.,  & Cevizci, S. et al. (2016). The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 33(5), 345-348. https://doi.org/10.5114/ada.2016.62840

Chicago

Kılıç, Sevilay, Selda Işık, Meliha Merve Hiz, Dilek Ülker Çakır, Hakan Türkön, Sibel Cevizci,  and Zerrin Ogretmen. 2016. "The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 33 (5): 345-348. doi:10.5114/ada.2016.62840.

Harvard

Kılıç, S., Işık, S., Hiz, M., Çakır, D., Türkön, H., Cevizci, S.,  and Ogretmen, Z. (2016). The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 33(5), pp.345-348. https://doi.org/10.5114/ada.2016.62840

MLA

Kılıç, Sevilay et al. "The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 33, no. 5, 2016, pp. 345-348. doi:10.5114/ada.2016.62840.

Vancouver

Kılıç S, Işık S, Hiz M, Çakır D, Türkön H, Cevizci S et al. The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2016;33(5):345-348. doi:10.5114/ada.2016.62840.

Introduction: Behçet’s disease (BD) is a chronic inflammatory disorder with endothelial dysfunction. Ischemia-modified albumin (IMA) is a marker used in the detection of diseases associated with oxidative stress, vascular endothelial cell dysfunction and ischemia. Mean platelet volume (MPV) signifies the platelet function and activity.

Aim: To show whether MPV and IMA are useful in revealing the oxidative stress and the risk of thrombosis in patients with BD.

Material and methods: Twenty-six patients with BD and 28 healthy volunteers as a control group over 18 years of age were included in the study. Serum IMA and MPV levels were analyzed in both groups.

Results: The mean MPV values were identified as 0.86 ±0.15 and 0.82 ±0.08 (in the BD and control groups, respectively; p = 0.188) and the mean IMA values were 9.39 ±0.73 and 9.17 ±1.09 (in the BD and control groups, respectively; p = 0.275). There were no statistically significant differences between the groups. The IMA values of BD patients who were in the active phase were significant as compared to inactive BD patients and control groups (p = 0.041). The IMA and MPV values of the thrombotic patients, non-thrombotic patients and control groups were not significant.

Conclusions: Ischemia-modified albumin may be a helpful marker of possible complications during an active period of BD.

keywords:

The ischemia modified albumin and mean platelet volume levels in patients with Behçet’s disease

Sevilay Kılıç , Selda Işık , Meliha Merve Hiz , Dilek Ülker Çakır , Hakan Türkön , Sibel Cevizci , Zerrin Ogretmen

Behçet’s disease, ischemia-modified albumin, mean platelet volume

Sevilay Kılıç

,

Selda Işık

,

Meliha Merve Hiz

,

Dilek Ülker Çakır

,

Hakan Türkön

,

Sibel Cevizci

,

Zerrin Ogretmen