eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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3/2012
vol. 9
 
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abstract:

The issue of cardio-renal syndrome and utility of acute kidney injury markers’ assessment in cardiac surgery practice

Łukasz Krzych
,
Maciej Wybraniec
,
Jerzy Chudek
,
Andrzej Bochenek

Kardiochirurgia i Torakochirurgia Polska 2012; 3: 305–313
DOI: https://doi.org/10.5114/kitp.2012.30841
Online publish date: 2012/10/01
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The recently established classification of cardio-renal syndrome eventually standardized the nomenclature concerning the interactions between pathology of the heart and kidney. Type 1 cardio-renal syndrome (CRS 1), in which the acute decompensation of the cardiovascular system triggers acute kidney injury (AKI), was found to be associated with poor outcome, especially in the setting of cardiac surgery. Early identification of the onset of AKI is limited on account of the current use of merely functional parameters, such as plasma creatinine concentration. Numerous studies are being performed to identify novel markers of AKI and evaluate their effectiveness. The protein NGAL (neutrophil gelatinase-associated lipocalin) is believed to be a good candidate for a sensitive and early indicator of AKI occurrence.
keywords:

cardio-renal syndrome, acute kidney injury, cardiac surgery, NGAL, perioperative care
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