The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine

Julia Szydlik; Jakub Nieznański; Konstancja Bałażyk; Jakub Pokrzywnicki; Ada Sawicka; Piotr Jankowski

doi:10.5114/aic.2023.129213

eISSN: 1897-4295
ISSN: 1734-9338

Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej

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abstract:

Original paper

The relation between uric acid level and blood pressure values among patients hospitalized in a department of internal medicine

Julia Szydlik

¹

,

Jakub Nieznański

¹

,

Konstancja Bałażyk

¹

,

Jakub Pokrzywnicki

¹

,

Ada Sawicka

²

,

Piotr Jankowski

^{2, 3}

Student Scientific Association of Geriatric Cardiology, Warsaw Medical University, Warsaw, Poland
Department of Internal Medicine and Geriatric Cardiology, Centre of Postgraduate Medical Education, Warsaw, Poland
Department of Epidemiology and Health Promotion, School of Public Health, Centre of Postgraduate Medical Education, Warsaw, Poland

Adv Interv Cardiol 2023; 19, 2 (72): 142–151

DOI: https://doi.org/10.5114/aic.2023.129213

Online publish date: 2023/06/30

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AMA

Szydlik J, Nieznański J, Bałażyk K, Pokrzywnicki J, Sawicka A, Jankowski P. The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2023;19(2):142-151. doi:10.5114/aic.2023.129213.

APA

Szydlik, J., Nieznański, J., Bałażyk, K., Pokrzywnicki, J., Sawicka, A.,  & Jankowski, P. (2023). The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 19(2), 142-151. https://doi.org/10.5114/aic.2023.129213

Chicago

Szydlik, Julia, Jakub Nieznański, Konstancja Bałażyk, Jakub Pokrzywnicki, Ada Sawicka,  and Piotr Jankowski. 2023. "The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine". Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej 19 (2): 142-151. doi:10.5114/aic.2023.129213.

Harvard

Szydlik, J., Nieznański, J., Bałażyk, K., Pokrzywnicki, J., Sawicka, A.,  and Jankowski, P. (2023). The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, 19(2), pp.142-151. https://doi.org/10.5114/aic.2023.129213

MLA

Szydlik, Julia et al. "The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine." Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej, vol. 19, no. 2, 2023, pp. 142-151. doi:10.5114/aic.2023.129213.

Vancouver

Szydlik J, Nieznański J, Bałażyk K, Pokrzywnicki J, Sawicka A, Jankowski P. The relation between uric acid level and blood pressure values among patients hospitalized in a department 
of internal medicine. Advances in Interventional Cardiology/Postępy w Kardiologii Interwencyjnej. 2023;19(2):142-151. doi:10.5114/aic.2023.129213.

Introduction:
The relationship between uric acid (UA) level and blood pressure (BP) is not clear, although most studies suggest BP reduction in patients treated with UA level lowering agents.

Aim:
The aim of the study was to evaluate the relationship between UA level and BP among patients hospitalized in a department of internal medicine. We also intended to investigate the relation between the allopurinol dose prescribed and BP.

Material and methods:
We reviewed hospital records of 561 patients (mean age: 65.46 ±17.46 years) hospitalized in a department of internal medicine, in whom UA level was determined on admission.

Results:
We did not find a significant correlation between UA level and BP values in the whole group, nor in patients not taking any BP-lowering or any UA-lowering drug. Multivariable analysis showed that allopurinol dose was not independently related to BP. Age (OR = 1.04, 95% CI: 1.03–1.06 per 1 year), diabetes (OR = 1.90, 95% CI: 1.14–3.16), stage 2 (OR = 4.96, 95% CI: 2.15–11.46) and stage 3 obesity (OR = 13.66, 95% CI: 5.90–31.60), both vs. patients without stage 2/3 obesity, but not UA level, were independently related to the diagnosis of hypertension.

Conclusions:
Our study does not confirm an independent relationship between UA level and BP nor between UA lowering and BP in a population of hospitalized patients.

keywords:

The relation between uric acid level and blood pressure values among patients hospitalized in a department of internal medicine

Julia Szydlik 1 , Jakub Nieznański 1 , Konstancja Bałażyk 1 , Jakub Pokrzywnicki 1 , Ada Sawicka 2 , Piotr Jankowski 2, 3

uric acid, hyperuricemia, blood pressure, hypertension, uric acid-lowering treatment

Julia Szydlik

¹

,

Jakub Nieznański

¹

,

Konstancja Bałażyk

¹

,

Jakub Pokrzywnicki

¹

,

Ada Sawicka

²

,

Piotr Jankowski

^{2, 3}