The role of NKT cells in the pathogenesis of atherosclerosis

Anna Wesołowska; Marzena Dworacka

eISSN: 2084-9877
ISSN: 1896-9666

Przegląd Kardiodiabetologiczny/Cardio-Diabetological Review

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3/2008
vol. 3

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abstract:

The role of NKT cells in the pathogenesis of atherosclerosis

Anna Wesołowska

,

Marzena Dworacka

Przegląd Kardiodiabetologiczny 2008; 3, 3: 213–216

Online publish date: 2008/10/20

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The development of atherosclerosis/macroangiopathy in the course of pre-diabetes and diabetes type 2 is closely related to immune-dependent deteriorations. The evaluation of atherosclerotic pathogenesis, especially its preclinical phases, seems to be an essential step on the way to successful prevention of atherosclerosis. Therefore NKT cells arouse our interest in their role in early phases of atherosclerosis. Immunomodulatory NKT cells combine properties of classical T lymphocytes and NK cells and current observations indicate their evident pro-atherogenic role in the vascular cell wall.

keywords:

The role of NKT cells in the pathogenesis of atherosclerosis

Anna Wesołowska , Marzena Dworacka

atherosclerosis, NKT cells, type 2 diabetes, pre-diabetes

Anna Wesołowska

,

Marzena Dworacka