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1/2007
vol. 109 abstract:
Original paper
The role of apoptosis in induction ocular changes in patients with cystic fibrosis
Małgorzata Mrugacz
1
,
Beata Żelazowska-Rutkowska
2
,
Alina Bakunowicz-Łazarczyk
1
,
Jolanta Wysocka
2
,
Maciej Kaczmarski
3
Klinika Oczna 2007, 109 (1): 22-24
Online publish date: 2007/03/23
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Purpose
To evaluate the concentration of sFas in tear film of cystic fibrosis patients Material and methods Tear samples were collected from 20 patients with cystic fibrosis and 20 patients from control group. The sFas levels were determined by immunoenzymatic assay ELISA. Results We found statistically increased levels of sFas in tear film of patients with cystic fibrosis compared with control group. Conclusions Apoptosis may play role in the pathogenesis of ocular changes in cystic fibrosis patients. The above results are important for the choice of the treatment of dry eye syndrome in patients with cystic fibrosis. keywords:
cystic fibrosis, apoptosis, sFas |
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POLSKI
