1. Aigner M, Treasure J, Kaye W, Kasper S. The WFSBP Task Force on Eating Disorders. World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for the Phar macological Treatment of Eating Disorders, World J. Biol. Psychiatry. 2011; 12: 400-443.
2.
Beier KT, Steinberg EE, DeLoach KE, Xie S, Miyamichi K, Schwarz L. Circuit architecture of VTA dopamine neurons revealed by systematic input-output mapping. Cell. 2015; 162: 622-634.
3.
Bello NT, Hajnal A. Dopamine and binge eating behaviors. Pharmacol. Biochem. Behav. 2010; 97: 25-33.
4.
Bonhaus DW, Weinhardt KK, Taylor M, DeSouza A, McNeeley PM, Szczepanski K, Fontana DJ, Trinh J, Rocha CL, Dawson MW, Flippin LA, Eglen RM. RS-102221: a novel high affinity and selective, 5-HT2C receptor antagonist. Neuropharma cology. 1997; 36(4-5): 621-629.
5.
Bubar MJ, Cunningham KA. Distribution of serotonin 5-HT2C receptors in the ventral tegmental area. Neuro science. 2007; 146: 286-297.
6.
Di Matteo V, Di Mascio M, Di Giovanni G, Eposito E: Acute administration of amitryptyline and mianserin increases dopmaine release in the rat nucelus accum-bens: possible involvement of serotonin2C receptors. Psychopharmacology. 2000; 150: 45-51.
7.
Farr OM, Sofopoulos M, Tsoukas MA, Dincer F, Thakkar B, Sahin-Efe A, Filippaios A, Bowers J, Srnka A, Gavrieli A, Ko BJ, Liakou C, Kanyuch N, Tseleni-Balafouta S, Mantzoros CS. GLP-1 receptors exist in the parietal cortex, hypothalamus and medulla of human brains and the GLP-1 analogue lira glutide alters brain activity related to highly desirable food cues in individuals with diabetes: a crossover, randomised, placebo-controlled trial. Diabetologia. 2016; 59(5): 954-965.
8.
Göke R , Larsen PJ , Mikkelsen JD , Sheikh SP. Distribution of GLP-1 binding sites in the rat brain: evidence that exendin-4 is a ligand of brain GLP-1 binding sites. Eur. J. Neurosci. 1995; 7(11): 2294-2300.
9.
Holt MK, Richards JE, Cook DR, Brierley DI, Williams DL, Reimann F, Gribble FM, Trapp S. Neurons in the Nucleus of the Solitary Tract Are the Main Source of Brain GLP-1, Mediate Stress-Induced Hypophagia, and Limit Unusually Large Intakes of Food. Diabetes. 2019; 68(1): 21-33.
10.
Holt MK, Trapp S.The physiological role of the brain GLP-1 system in stress. Cogent. Biol. 2016; 2(1): 1229086.
11.
Kaye W. Neurobiology of anorexia and bulimia nervosa. Physiol. Behav. 2008; 94: 121-135.
12.
Koch S, Perry KW, Nelson DL, Conway RG, Threlkeld PG, Bymaster FP. R-fluoxetine increases extracellular DA, NE, as well as 5-HT in rat refrontal cortex and hypothalamus: an in vivo microdialysis and receptor binding study. Neu ropsychopharmacology. 2002; 27(6): 949-959.
13.
Lefort S, Tschöp MH, García-Cáceres C. A Synaptic Basis for GLP-1 Action in the Brain. Neuron. 2017; 96(4): 713-715.
14.
Leon RM, Borner T, Reiner DJ, Stein LM, Lhamo R, De Jonghe BC, Hayes MR. Hypophagia induced by hindbrain serotoninis mediated through central GLP-1 signaling and involves 5-HT2C and 5-HT3 receptor activation. Neuropsychophar macology. 2019; 44(10): 1742-1751.
15.
Meyer-Gerspach AC, Ly HG, Borgwardt S, Dupont P, Beglin ger C, Van Oudenhove L, Wölnerhanssen BK. Endogenous GLP-1 alters postprandial functional connectivity between homeostatic and reward-related brain regions involved in regulation of appetite in healthy lean males: A pilotstudy. Diabetes. Obes. Metab. 2018; 20(10): 2330-2338.
16.
Pannacciulli N, Le DS, Salbe AD, Chen K, Reiman EM, Tataran ni PA, Krakoff J. Postprandial glucagon-like peptide-1 (GLP-1) response is positively associated with changes in neuronal activity of brain areas implicated in satiety and food intake regulation in humans. Neuroimage. 2007; 35(2): 511-517.
17.
Ripken D, van der Wielen N, Wortelboer HM, Meijerink J, Witkamp RF, Hendriks HF. Nutrient-induced glucagon like peptide-1 release is modulated by serotonin. J. Nutr. Bio chem. 2016; 32: 142-150.
18.
Roth BL, Kroeze WK. Screening the receptorome yields va lidated molecular targets for drug discovery. Curr. Pharm. Des. 2006; 12(14): 1785-1795.
19.
Szczypka MS, Rainey MA, Palmiter RD. Dopamine is required for hyperphagia in Lep(ob/ob) mice. Nat. Genet. 2000; 25: 102-104.
20.
van Bloemendaal L, IJzerman RG, Ten Kulve JS, Barkhof F, Konrad RJ, Drent ML, Veltman DJ, Diamant M. GLP-1 receptor activation modulates appetite- and reward-related brain areas in humans. Diabetes. 2014; 63(12): 4186-4196.
21.
van Bloemendaal L, Veltman DJ, ten Kulve JS, Drent ML, Barkhof F, Diamant M, IJzerman RG. Emotional eating is associated with increased brain responses to food-cues and reduced sensitivity to GLP-1 receptor activation. Obesity (Silver Spring). 2015; 23(10): 2075-2082.
22.
Wong DT, Horng JS, Bymaster FP, Hauser KL, Molloy BB (Au gust 1974). A selective inhibitor of serotonin uptake: Lilly 110140, 3-(p-trifluoromethylphenoxy)-N-methyl-3-pheny lpropylamine. Life Sciences. 15 (3): 471-479.
23.
Xu P, He Y, Cao X, Valencia-Torres L, Yan X, Saito K, Wang C, Yang Y, Hinton A Jr, Zhu L, Shu G, Myers MG Jr, Wu Q, Tong Q, Heisler LK, Xu Y. Activation of Serotonin 2C Receptors in Dopamine Neurons Inhibits Binge-like Eating in Mice. Biol. Psychiatry. 2017; 81(9): 737-747.
