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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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3/2007
vol. 109
 
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abstract:
Review paper

The role of chemokines in ocular diseases. Part. I. Structure and role of chemokines in chosen diseases

Roman Malesiński
1
,
Małgorzata Mrugacz
2
,
Alina Bakunowicz-Łazarczyk
2

  1. Oddział Chorób Oczu Wojewódzkiego Szpitala Zespolonego w Białymstoku
  2. Klinika Okulistyki Dziecięcej Akademii Medycznej w Białymstoku
Klinika Oczna 2007, 109 (3): 340-344
Online publish date: 2007/09/27
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The chemokines are a large family of chemotactic cytokines produced by leucocytes, fibroblasts, keratynocytes and the others tissue cells. Chemokines stimulate and regulate leucocytes migration in inflammations. All the described human chemokines

transmit intracellular signals by binding and activating specific G protein-coupled receptors on the cell surfaces of their target cells. Chemokines are involved in variety of inflammatory and autoimmune diseases.
keywords:

chemokines, chemotaxis, antagonists

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