The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function

Bogusław Nedoszytko; Małgorzata Sokołowska-Wojdyło; Joanna Renke; Magdalena Lange; Piotr Trzonkowski; Michał Sobjanek; Aneta Szczerkowska-Dobosz; Marek Niedoszytko; Aleksandra Górska; Jan Romantowski; Jarosław Skokowski; Leszek Kalinowski; Roman Nowicki

doi:10.5114/pdia.2017.67053

eISSN: 2299-0046
ISSN: 1642-395X

Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii

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abstract:

Review paper

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function

Bogusław Nedoszytko

,

Małgorzata Sokołowska-Wojdyło

,

Joanna Renke

,

Magdalena Lange

,

Piotr Trzonkowski

,

Michał Sobjanek

,

Aneta Szczerkowska-Dobosz

,

Marek Niedoszytko

,

Aleksandra Górska

,

Jan Romantowski

,

Jarosław Skokowski

,

Leszek Kalinowski

,

Roman J. Nowicki

Adv Dermatol Allergol 2017; XXXIV (6): 517-525

DOI: https://doi.org/10.5114/pdia.2017.67053

Online publish date: 2017/12/31

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AMA

Nedoszytko B, Sokołowska-Wojdyło M, Renke J, et al. The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2017;34(6):517-525. doi:10.5114/pdia.2017.67053.

APA

Nedoszytko, B., Sokołowska-Wojdyło, M., Renke, J., Lange, M., Trzonkowski, P.,  & Sobjanek, M. et al. (2017). The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 34(6), 517-525. https://doi.org/10.5114/pdia.2017.67053

Chicago

Nedoszytko, Bogusław, Małgorzata Sokołowska-Wojdyło, Joanna Renke, Magdalena Lange, Piotr Trzonkowski, Michał Sobjanek,  and Aneta Szczerkowska-Dobosz et al. 2017. "The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function". Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii 34 (6): 517-525. doi:10.5114/pdia.2017.67053.

Harvard

Nedoszytko, B., Sokołowska-Wojdyło, M., Renke, J., Lange, M., Trzonkowski, P., Sobjanek, M., Szczerkowska-Dobosz, A., Niedoszytko, M., Górska, A., Romantowski, J., Skokowski, J., Kalinowski, L.,  and Nowicki, R. (2017). The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, 34(6), pp.517-525. https://doi.org/10.5114/pdia.2017.67053

MLA

Nedoszytko, Bogusław et al. "The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function." Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii, vol. 34, no. 6, 2017, pp. 517-525. doi:10.5114/pdia.2017.67053.

Vancouver

Nedoszytko B, Sokołowska-Wojdyło M, Renke J, Lange M, Trzonkowski P, Sobjanek M et al. The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function. Advances in Dermatology and Allergology/Postępy Dermatologii i Alergologii. 2017;34(6):517-525. doi:10.5114/pdia.2017.67053.

Regulatory T cells (Tregs) represent a cell type that promotes immune tolerance to autologous components and maintains immune system homeostasis. The abnormal function of Tregs is relevant to the pathogenesis of several skin diseases like psoriasis, atopic dermatitis, systemic lupus erythematosus, cutaneous T-cell lymphomas, and skin cancer and is also important in rheumatoid arthritis, diabetes and other autoimmune diseases. In this review, we will summarize the role of mutations and/or polymorphisms of genes involved in Tregs development, and functions in the pathogenesis of selected skin diseases.

keywords:

The role of regulatory T cells and genes involved in their differentiation in pathogenesis of selected inflammatory and neoplastic skin diseases. Part III: Polymorphisms of genes involved in Tregs’ activation and function

Bogusław Nedoszytko , Małgorzata Sokołowska-Wojdyło , Joanna Renke , Magdalena Lange , Piotr Trzonkowski , Michał Sobjanek , Aneta Szczerkowska-Dobosz , Marek Niedoszytko , Aleksandra Górska , Jan Romantowski , Jarosław Skokowski , Leszek Kalinowski , Roman J. Nowicki

Tregs gene polymorphisms, skin diseases

Bogusław Nedoszytko

,

Małgorzata Sokołowska-Wojdyło

,

Joanna Renke

,

Magdalena Lange

,

Piotr Trzonkowski

,

Michał Sobjanek

,

Aneta Szczerkowska-Dobosz

,

Marek Niedoszytko

,

Aleksandra Górska

,

Jan Romantowski

,

Jarosław Skokowski

,

Leszek Kalinowski

,

Roman J. Nowicki