The role of the microbiota in connective tissue diseases

Aleksandra Fijałkowska; Agnieszka Żebrowska

doi:10.5114/dr.2022.126601

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

6/2022
vol. 109

Send email

Copy url:

abstract:

Review article

The role of the microbiota in connective tissue diseases

Aleksandra Fijałkowska

¹

,

Agnieszka Żebrowska

¹

Department of Dermatology and Venereology, Medical University of Lodz, Lodz, Poland; Katedra i Klinika Dermatologii i Wenerologii, Uniwersytet Medyczny w Łodzi, Łódź, Polska

Dermatol Rev/Przegl Dermatol 2022, 109, 417-426

DOI: https://doi.org/10.5114/dr.2022.126601

Online publish date: 2023/04/21

View full text Get citation

PlumX metrics:

Connective tissue diseases are a group of diseases with a complex etiology characterized by abnormal activity of the immune system. In the last decade, the role of the gut microbiota as a potential modulator of diseases such as systemic lupus erythematosus and systemic sclerosis has attracted significant interest. Deviations in the composition of the intestinal microbiota cause a number of unfavorable consequences that may lead to progression of connective tissue diseases. So far, there is no clear knowledge whether dysbiosis induces the development of these diseases or is a secondary phenomenon to pathological changes occurring in the body. Research is currently underway to develop innovative therapeutic strategies based on regulation of the composition of intestinal bacteria. This may allow limiting the use of basic immunosuppressive drugs associated with high risk of side effects.

keywords:

The role of the microbiota in connective tissue diseases

Aleksandra Fijałkowska 1 , Agnieszka Żebrowska 1

connective tissue diseases, microbiome, dysbiosis

Aleksandra Fijałkowska

¹

,

Agnieszka Żebrowska

¹