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eISSN: 2084-9893
ISSN: 0033-2526
Dermatology Review/Przegląd Dermatologiczny
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SCImago Journal & Country Rank
5/2021
vol. 108
 
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abstract:
Review article

The significance of secukinumab in the treatment of plaque psoriasis

Marta Kasprowicz-Furmańczyk
1
,
Agnieszka Owczarczyk-Saczonek
1

  1. The Municipal Polyclinic Hospital, Olsztyn, Poland
Dermatol Rev/Przegl Dermatol 2021, 108, 372–384
Online publish date: 2022/02/07
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Psoriasis is a chronic inflammatory skin disease that affects approximately 1–3% of the general population in Poland. It is estimated that in 70–80% of patients skin lesions are mild and require only topical medications. In severe plaque psoriasis, classic treatments often lead to a loss of efficacy, adverse effects or insufficient treatment effect, therefore it is necessary to search for new therapeutic methods. Multiple studies show that secukinumab, a fully human monoclonal antibody that selectively neutralizes interleukin-17A (IL-17A), has significant efficacy in the treatment of moderate to severe psoriasis, demonstrating a rapid onset of action and sustained response with a good safety profile. The role of secukinumab in the treatment of plaque psoriasis is discussed in this article.
keywords:

secukinumab, psoriasis, biological treatment



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