The thin red line – postmenopausal abnormal uterine bleeding with endometrial thickness less than 4 mm

Magdalena Piróg; Olga Kacalska-Janssen; Tomasz Bereza; Robert Jach

doi:10.5114/wo.2019.83816

eISSN: 1897-4309
ISSN: 1428-2526

Contemporary Oncology/Współczesna Onkologia

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1/2019
vol. 23

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abstract:

Original paper

The thin red line – postmenopausal abnormal uterine bleeding with endometrial thickness less than 4 mm

Magdalena Piróg

¹

,

Olga Kacalska-Janssen

¹

,

Tomasz Bereza

¹

,

Robert Jach

¹

Department of Gynecological Endocrinology, Jagiellonian University Medical College, Krakow, Poland

Contemp Oncol (Pozn) 2019; 23 (1): 43-46

DOI: https://doi.org/10.5114/wo.2019.83816

Online publish date: 2019/04/05

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Aim of the study
To evaluate the risk of endometrial malignancy in postmenopausal women with abnormal uterine bleeding (AUB) with endometrial thickness ≤ 4 mm.

Material and methods
Histological assessment of endometrial samples obtained via hysteroscopy or curettage was performed in 57 women.

Results
Women with premalignancy or malignancy (24.6%) had higher endometrial thickness (by 9.7%, p = 0.01) compared to women with benign condition. Out of 12 women with atypical hyperplasia (21.1%), 5 women (8.8%) were diagnosed with simple and 7 women (12.3%) had complex hyperplasia, whereas 2 (3.5%) were diagnosed with malignancy.

Conclusions
Postmenopausal women with AUB and endometrial echo ≤ 4 mm are less likely to have a malignant condition. However, the role of histological evaluation cannot be undermined, especially in women at high risk of endometrial cancer, and routine endometrial biopsy should be considered. We recommend a change in the cut-off to 2 mm in routine practice.

keywords:

The thin red line – postmenopausal abnormal uterine bleeding with endometrial thickness less than 4 mm

Magdalena Piróg 1 , Olga Kacalska-Janssen 1 , Tomasz Bereza 1 , Robert Jach 1

endometrial thickness, endometrial cancer, postmenopausal bleeding, abnormal uterine bleeding

Magdalena Piróg

¹

,

Olga Kacalska-Janssen

¹

,

Tomasz Bereza

¹

,

Robert Jach

¹