eISSN: 2354-0265
ISSN: 2353-6942
Health Problems of Civilization Physical activity: diseases and issues recognized by the WHO
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1/2019
vol. 13
 
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abstract:
Original paper

The use of anti- C6VlsE in the assessment of the effectivness of Lyme disease treatment – a preliminary report

Mariia Shkilna
1
,
Małgorzata Tokarska-Rodak
2
,
Anna Pańczuk
3
,
Svitlana Smiyan
1
,
Mykhailo Andreychyn
1
,
Ivan Klishch
1
,
Mykhailo Korda
1

  1. Ivan Horbachevsky Ternopil State Medical University, Ukraine
  2. Institute of Health Sciences, Pope John Paul II State School of Higher Education in Biała Podlaska, Poland
  3. Institute of Physical Education and Physiotherapy, Pope John Paul II State School of Higher Education in Biała Podlaska, Poland
Health Prob Civil. 2019; 13(1): 83-91
DOI: https://doi.org/10.5114/hpc.2019.81106
Online publish date: 2019/01/28
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Background
The aim of this study was to evaluate the dynamics of changes in IgG anti-C6VlsE concentration in patients treated for Lyme borreliosis in relation to clinical manifestations of the disease.

Material and methods
The study group consisted of 20 patients from Ternopil and surrounding areas (Western Ukraine) with clinical symptoms of Lyme borreliosis. IgG anti-C6VlsE was measured three times: before starting the patients on antibiotic therapy, immediately after its completion and 3-4 months after the end of antibiotic therapy.

Results
In 40% of the patients the IgG anti-C6VlsE concentration decreased 3-4 months after the treatment, but only in half of them it was associated with elimination of symptoms. 60% of patients did not show any tendency to decrease in IgG anti-C6VlsE concentrations after 3-4 months after the treatment, and 25% of patients in this group had an improvement in health condition.

Conclusions
It cannot be excluded that IgG anti-C6VlsE may be important in the serological evaluation of the efficacy of Lyme borreliosis treatment, especially in early stage patients. However, this requires further research, which should be extended to a larger group of patients. It is also important that the assessment of anti-C6VlsE antibody concentration should be performed additionally for a period longer than 4 months from the end of antibiotic therapy.

keywords:

VlsE, Borrelia burgdorferi, Lyme borreliosis, Ukraine

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