en POLSKI
eISSN: 2300-8660
ISSN: 0031-3939
Pediatria Polska - Polish Journal of Paediatrics
Current issue Archive Manuscripts accepted About the journal Editorial board Abstracting and indexing Contact Instructions for authors Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
Search
Editorial Policies
Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

1/2024
vol. 99
 
Share:
Send email
Share:
abstract:
Review paper

There’s something in the air – the role of volatile organic compounds in exhaled air in the diagnosis and treatment of asthma in children

Katarzyna Gmachowska
1, 2
,
Aleksandra Jarek
3
,
Joanna Jerzyńska
1
,
Paweł Majak
4
,
Daniela Podlecka
1

  1. Department of Pediatric and Allergy, Korczak Pediatric Center, Copernicus Hospital, Medical University of Łódź, Poland
  2. International Doctoral Scholl, Medical University of Łódź, Poland
  3. Medical University of Łódź, Poland
  4. Department of Pulmonology, Korczak Pediatric Center, Copernicus Hospital, Łódź, Poland
Pediatr Pol 2024; 99 (1): 61-65
DOI: https://doi.org/10.5114/polp.2024.135829
Online publish date: 2024/03/04
View full text Get citation
 
PlumX metrics:
Bronchial asthma, which is the most common chronic disease of the respiratory system, causes significant diagnostic problems in younger children due to the difficulty of performing typical respiratory function tests, including spirometry. This problem is especially important for paediatricians, allergists, and pulmonologists. A new, promising method of objectifying allergic inflammation in the respiratory tract is the measurement of volatile organic compounds (VOCs) in exhaled air. They are formed during the metabolic processes of the body’s cells and the microorganisms that inhabit it. Clinical benefits of the VOC profile have been proven in differentiating asthma phenotypes, monitoring its course, predicting exacerbations, and responding to treatment. However, further studies are needed to standardise this process and establish reference standards. The aim of this study is to review the latest literature on the usefulness of VOC profiles in exhaled air and the composition of the microbiome in children with bronchial asthma.
keywords:

volatile organic compounds (VOCs), asthma, children’s allergic diseases