twitter
en POLSKI
eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
Current issue Archive Videos Articles in press About the journal Supplements Editorial board Reviewers Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures
Editorial System
Submit your Manuscript
SCImago Journal & Country Rank
2/2007
vol. 109
 
Share:
Share:
abstract:
Original paper

Transpupillary thermotherapy in exudative age-related macular degeneration

Agnieszka Kubicka-Trząska
1
,
Maria Starzycka
1
,
Ewa Ortyl
1
,
Alina Górniak-Bednarz
1
,
Izabella Karska-Basta
1

  1. Klinika Okulistyki i Onkologii Okulistycznej Katedry Okulistyki Collegium Medicum Uniwersytetu Jagiellońskiego w Krakowie
Klinika Oczna 2007, 109 (2): 142-145
Online publish date: 2007/06/12
View full text Get citation
 
Purpose
Assessment of TTT results in patients with exudative age-related macular degeneration.

Material and methods
The study comprised of 65 patients (73 eyes), in age 50-84 years (average age-75 yrs). The diagnosis of exudative AMD was established on the basis of fundus examination and fluorescein angiography (FA) and in some cases on indocyanine green angiography. The baseline visual acuity (VA) ranged from counting fingers at 50 cm to 0.8. In 31 (42.5%) eyes occult CNV, in 11 (15%) minimally classic CNV and in 31 (42.5%) eyes predominantly classic CNV were observed. Subfoveal CNV was present in 70 (95.9%) eyes and perifoveal in 3 (4.1%). TTT was delivered using a diode laser at 810 nm wavelength, a spot size of 1.2 to 4.5 mm and a duration of 60 seconds for each spot with power settings between 320 – 800 mW. Followup examinations were carried out every 10-12 weeks. In cases with persistent leakage from CNV in late frames of FA a retreatment was performed. The follow-up period ranged from 6 to 28 months (average – 9.8 months).

Results
Visual acuity improved in 22 (30.1%) eyes, stabilized in 34 (46.6%) and deteriorated in 17 (23.3%). Fluorescein angiography showed no CNV leakage in 58 (79.5%) eyes. In 56 (71.8%) with regression of leakage in fluorescein angiography improvement or stabilization of visual acuity was detected. Subretinal haemorrhages after TTT were observed in 4 eyes (5.5%). At the end of the follow-up period fibrosis of CNV was detected in 12 eyes (16.4%).

Conclusions
TTT is effective and safe method of treatment of occult and classic CNV in a course of wet AMD. In a majority of cases TTT results in total or partial regression of CNV and stabilization of visual acuity.

keywords:

transpupillary thermotherapy, exudative age-related macular degeneration, choroidal neovascularization

Quick links
© 2024 Termedia Sp. z o.o.
Developed by Bentus.