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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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1/2013
vol. 115
 
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abstract:
Case report

Treatment of cystoid macular edema with bevacizumab in course of Irvine-Gass syndrome

Bartosz Izdebski
1
,
Zofia Michalewska
1, 2
,
Krzysztof Dzięgielewski
2
,
Jerzy Nawrocki
1, 2
,
Dominik Odrobina
1, 2

  1. Oddział Okulistyki III Szpitala Miejskiego im. Karola Jonschera w Łodzi
  2. Klinika Okulistyczna „Jasne Błonia” w Łodzi
Klinika Oczna 2013, 115 (1): 61-64
Online publish date: 2013/03/28
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Purpose: To determine clinical effect of intravitreal bevacizumab (Avastin) in patients with cystoid macular edema after cataract surgery.

Material and methods: Four eyes of four patients treated with 1 intravitreal injection of 1.25 mg Avastin. In three cases duration of cystoid macular edema was less then 4 months, in one eye cystoid macular edema was chronic (more than 4 months). Visual acuity and clinical effect in spectral optical coherence tomography (central retinal thickness and fovea anatomy) was examined before and after intravitreal injection.

Results: Visual acuity improved in 3 of 4 patients. In acute cystoid macular edema final visual acuity was 0.8–0.9, in chronic cystoid macular edema patient visual acuity improved from 0.05 to 0.2. In 3 of 4 patients central retinal thickness decreased and fovea anatomy was normalized. In patient with no clinical and anatomical improvement spectral optical coherence tomography examination revealed epiretinal membrane.

Conclusions: Intravitreal Avastin may be successful treatment in most Irvine-Gass syndrome cases. The condition that exclude patients from bevacizumab treatment is horizontal (epiretinal membrane), and vertical traction revealed in spectral optical coherence tomography.
keywords:

pseudophakic cystoid macular edema, Irvine-Gass syndrome, bevacizumab, spectral optical coherent tomography, epiretinal membrane

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