Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw

Beata Wolska-Kuśnierz; Małgorzata Pac; Barbara Pietrucha; Edyta Heropolitańska-Pliszka; Maja Klaudel-Dreszler; Magdalena Kurenko-Deptuch; Hanna Gregorek; Jacek Michałkiewicz; Barbara Piątosa; Ewa Bernatowska

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ISSN: 1426-3912

Central European Journal of Immunology

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3-4/2005
vol. 30

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abstract:

Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw

Beata Wolska-Kuśnierz

,

Małgorzata Pac

,

Barbara Pietrucha

,

Edyta Heropolitańska-Pliszka

,

Maja Klaudel-Dreszler

,

Magdalena Kurenko-Deptuch

,

Hanna Gregorek

,

Jacek Michałkiewicz

,

Barbara Piątosa

,

Ewa Bernatowska

(Centr Eur J Immunol 2005; 30 (3-4): 104-114)

Online publish date: 2006/10/10

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AMA

Wolska-Kuśnierz B, Pac M, Pietrucha B, et al. Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw. Central European Journal of Immunology. 2005;30(3):3-4.

APA

Wolska-Kuśnierz, B., Pac, M., Pietrucha, B., Heropolitańska-Pliszka, E., Klaudel-Dreszler, M.,  & Kurenko-Deptuch, M. et al. (2005). Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw. Central European Journal of Immunology, 30(3), 3-4.

Chicago

Wolska-Kuśnierz, Beata, Małgorzata Pac, Barbara Pietrucha, Edyta Heropolitańska-Pliszka, Maja Klaudel-Dreszler, Magdalena Kurenko-Deptuch,  and Hanna Gregorek et al. 2005. "Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw". Central European Journal of Immunology 30 (3): 3-4.

Harvard

Wolska-Kuśnierz, B., Pac, M., Pietrucha, B., Heropolitańska-Pliszka, E., Klaudel-Dreszler, M., Kurenko-Deptuch, M., Gregorek, H., Michałkiewicz, J., Piątosa, B.,  and Bernatowska, E. (2005). Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw. Central European Journal of Immunology, 30(3), pp.3-4.

MLA

Wolska-Kuśnierz, Beata et al. "Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw." Central European Journal of Immunology, vol. 30, no. 3, 2005, pp. 3-4.

Vancouver

Wolska-Kuśnierz B, Pac M, Pietrucha B, Heropolitańska-Pliszka E, Klaudel-Dreszler M, Kurenko-Deptuch M et al. Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw. Central European Journal of Immunology. 2005;30(3):3-4.

Nine hundred and forty-six cases of primary immunodeficiency diseases were diagnosed in the Department of Immunology of the Children’s Memorial Health Institute in Warsaw during 1980-2006. The highest frequency was that of antibody immunodeficiencies: 547 (57.8%). Predominantly T cell deficiencies were recognised in 80 (8.5%) children. In 29 children severe combined immunodeficiencies with different genetic defects were diagnosed, and in 18 of them hematopoietic stem cell transplantation was done. In the group of phagocytic disorders (95; 10% of patients), neutropenia was the most common - 46 cases, followed by chronic granulomatous diseased recognised in 41 patients. In the group of other well-defined PIDs - immunodeficiencies associated with chromosomal instability were the most common (152; 16% of patients). Ataxia – teleangiectasia was diagnosed in 92 cases and, next, Nijmegen Breakage syndrome in 57 children. Hyper IgE syndrome was diagnosed in 22 patients, and Wiskott-Aldrich syndrome in 19 boys.

keywords:

Twenty five years of investigations into primary immunodeficiency diseases in the Department of Immunology, The Children’s Memorial Health Institute, Warsaw

Beata Wolska-Kuśnierz , Małgorzata Pac , Barbara Pietrucha , Edyta Heropolitańska-Pliszka , Maja Klaudel-Dreszler , Magdalena Kurenko-Deptuch , Hanna Gregorek , Jacek Michałkiewicz , Barbara Piątosa , Ewa Bernatowska

primary immunodeficiencies, T cells defects, B cells defects, phagocytic defects, haematopoietic stem cell transplantation

Beata Wolska-Kuśnierz

,

Małgorzata Pac

,

Barbara Pietrucha

,

Edyta Heropolitańska-Pliszka

,

Maja Klaudel-Dreszler

,

Magdalena Kurenko-Deptuch

,

Hanna Gregorek

,

Jacek Michałkiewicz

,

Barbara Piątosa

,

Ewa Bernatowska