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ISSN: 1233-9687
Polish Journal of Pathology
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1/2017
vol. 68
 
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abstract:
Case report

Two neoplasms rich in small lymphocytes, B1B2 thymoma and small lymphocytic lymphoma, intermingled in one tumor mass. A case report

Malgorzata Szolkowska
,
Renata Langfort
,
Sebastian Winiarski
,
Jacek Zaremba
,
Monika Prochorec-Sobieszek
,
Grzegorz Rymkiewicz
,
Piotr Jaskiewicz
,
Dariusz M. Kowalski

Pol J Pathol 2017; 68 (1): 75-81
DOI: https://doi.org/10.5114/pjp.2017.67620
Online publish date: 2017/05/23
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We present a case of a 52-year-old man with myasthenia gravis and a mediastinal tumor who was admitted to our hospital for surgical treatment. The pathologic examination of the resected tumor revealed a very rare case of a collision tumor: a B1B2 thymoma and a small lymphocytic lymphoma. Flow cytometry of the peripheral blood revealed the presence of a small number of leukemic cells. After postoperative irradiation of the mediastinum and chemotherapy a complete response in both diseases was achieved. The case confirms that a pathologist should always be aware that two different neoplasms can coexist in rare cases.
keywords:

thymoma, small lymphocytic lymphoma, mediastinal tumors, immunohistochemistry, flow cytometry
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