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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
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SCImago Journal & Country Rank
3/2008
vol. 110
 
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abstract:
Original paper

Value of mfVEP test in pituitary tumors diagnosis

Anna Piekarska
1
,
Wojciech Lubiński
1
,
Wojciech Gosławski
1
,
Wiesława Wieliczko
2
,
Anhelli Syrenicz
3
,
Tomasz Olszowski
4
,
Danuta Karczewicz
1

  1. Z Katedry i Kliniki Okulistyki Pomorskiej Akademii Medycznej w Szczecinie
  2. Z Wojewódzkiej Poradni Endokrynologicznej w Szczecinie
  3. Z Kliniki Endokrynologii, Nadciśnienia Tętniczego i Chorób Przemiany Materii Pomorskiej Akademii Medycznej w Szczecinie
  4. Z Zakładu Higieny i Epidemiologii Pomorskiej Akademii Medycznej w Szczecinie
Online publish date: 2008/09/15
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Purpose: To evaluate the mfVEP test in detection of the optic nerve neuropathy in pituitary tumors.

Material and methods: We examined 30 eyes of 15 patients with confirmed by MRI pituitary tumors (7 patients with macroadenomas and 8 patients with microadenomas). In all patients the routine ophthalmologic examination, multifocal visual evoked

potentials (mfVEP) and standard static perimetry (central 24-2 threshold), were performed. The control group consisted of 30

eyes of 15 healthy persons.

Results: In 53% (16/30) of eyes manifested changes in static perimetry and/or in mfVEP test. In 13% (4/30) of eyes abnormal

static perimetry and mfVEP were simultaneously observed. The only mfVEP abnormalities were the most frequent feature and

were observed in 30% (9/30) of eyes. Only abnormal static perimetry results were observed in 10% (3/10) of eyes. In those

eyes in related areas of mfVEP recordings the mean peak-to-peak amplitude was significantly reduced compare to the control

group. In mfVEP test statistically significant peak-to-peak amplitude reduction was observed in superotemporal quadrants in

comparison to the control group (p < 0.009).

Conclusions: MfVEP can be useful test in the optic nerve dysfunction/ neuropathy diagnosis in patients with pituitary tumors.
keywords:

pituitary tumors, mfVEP, static perimetry

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