Zależności pomiędzy siedzącym stylem życia a zdrowiem człowieka w świetle badań PONS-Zdrowe Kielce

Introduction

It is well known that regular physical activity results in numerous physiological, psychological, and social benefits, both immediate and long-term. The definition of physical activity is of particular importance to the threats that the modern world poses to a man. Civilization, with its obvious benefits and achievements, became the cause of the development of many diseases collectively referred to as civilization diseases, i.e. obesity, coronary heart disease, diabetes, and cancer. Throughout the twentieth century, the presence of physical labor decreased by around 80% for the benefit of mental work [1, 2].
Nowadays, an adult spends 50–60% of his time during the day sitting. The term “sedentary” comes from the Latin “sedere” (to sit), and can be operationally defined as any waking sitting or lying behavior with low-energy expenditure. This operational definition broadly fits the commonly cited technical definition of < 1.5 metabolic equivalent units. Therefore, the term “sedentary behavior” typically refers to sitting/lying behavior rather than a simple absence of MVPA (moderate-to-vigorous intensity physical activity).
Eliminating these behaviors and promoting active lifestyles will be a factor delaying the occurrence of physical weakness and diseases, thus significantly reducing the cost of health care [3].

Aim of the research

The evaluation of the prevalence of sedentary life among the inhabitants of the city of Kielce, taking into account gender, education, body mass index (BMI), and civilization diseases.

Material and methods

The analysis included the data from the PONS-Healthy Kielce study. The study was conducted in 2012-2013. The analysis used the data related to gender, education, and the values of anthropometric indicators such as BMI, WHR, and WC derived from 4,777 (1,613 males and 3,164 females) study participants. The age of the participants ranged from 37 to 66 years (mean age, 56.3 years).
The largest group of the study participants declared the completion of secondary education (46%) and higher education (35%) (3% – primary, 12% – vocational, 4% – uncompleted university). Approximately 75% of the participants were married and nearly 7% were single.
The largest group of the study participants was represented by pensioners (31%) and persons employed in companies on the basis of an employment contract (44%). Most of them indicated working as “specialists” (34%), followed by “office workers” (17%), “government representatives, senior officials and managers” (13%), and “personal service workers and sales specialists” (13%).
Body weight was assessed using body composition analyzer TANITA BC 554. BMI of the Healthy Kielce study participants was calculated based on anthropometric measurements of height and weight, as the ratio of body weight (kg)/height (m2). The values of a continuous variable of BMI of the study participants were divided into 3 categories. Based on WHO guidelines, equally for men and women, normal weight patients reported BMI < 25 kg/m2, overweight patients – 25 kg/m2 ≥ BMI < 30 kg/m2, obese patients – BMI ≥ 30 kg/m2. The WHR value was calculated on the basis of the waist/hip circumference. The categories of WHR for women and men, respectively, were qualified based on its value (standard WHR < 0.8/0.94; abdominal obesity WHR ≥ 0.8/0.94). The categories of WC for men and women were set based on waist circumference (WC standard value < 88/102; abdominal obesity WC ≥ 88/102).
The results of the average BMI of the study group were 27.78 kg/m2. Normal BMI was related to 27%, whereas overweight and obesity to 56% and 27% of the study participants. 30% of the participants reported standard WHR, and 70% reported abdominal obesity. Standard WC was reported in 59.7% of cases.
38% of the study participants declared diagnosed with hypertension, 7% heart failure, and 9% coronary heart disease. 1.5% of participants suffered a stroke and 5% had diabetes. Asthma was diagnosed in 4% of participants, chronic obstructive pulmonary disease (COPD) in 0.7%, and cancer in 3.4%. Most common cancers were located in the “chest” (24%) and “the cervix, the stem, the ovary” (21%).
The questionnaire also included questions about sedentary lifestyle: the amount of time per week spent sitting on weekdays (min/day), holidays (min/day), the total sitting time (min/week), the average sitting time (min/day), the total sitting time including travel time (min/week), and the time spent watching television (hrs/week).
The analysis of the results was performed using the statistical package PQStat ver. 1.6. The differences in the time spent sitting, depending on the groups, were analyzed using Student’ t-test (in order to compare two groups) or one-way ANOVA (in order to compare more groups k > 2). The test probability of p < 0.05 was regarded as statistically significant, and the test probability of p < 0.01 was regarded as highly statistically significant.
Due to the size of the group, parametric tests were used to evaluate the differences between the analyzed groups. Homogeneity of variance was tested in groups. In the case of non-homogeneity, correction was made, and the results were tested without correction and after it. The lack of information about the use of the post-hoc test and the presence of the results of this test in the Tables is due to the ranking nature of the grouping scales, which allows them to be sorted in increasing order. If the result shows that there were statistically significant differences, information on the occurrence of the trend was reported (Table 1).

Results

The average time spent sitting on weekdays was 305.5 min/day (SD 164.6) and at weekends – 257.3 min/day (SD 128.5). The average total sitting time was 2,006.7 min/week (SD 960.4) (33.4 hrs/week; SD 160.0). The average of the average sitting time was 286.7 min/day (SD, 137.2), and total sitting time including travel time was 2,049.4 min/week (SD 966.0). The largest group of participants (38.7%) declared that they spent 11–20 hours per week watching TV.
In the case of the time spent sitting on days off, the total, average sitting time, the total sitting time including travel time as well as the time spent watching TV, the difference between the genders was highly statistically significant (p < 0.01) and higher scores related to men (Table 2).
The time spent sitting on weekdays was highly statistically significantly different (p < 0.01) depending on education, and the results increased with the higher level of education. In the case of time spent in a sitting position on weekends, the difference was not significant (p > 0.05). Total and average sitting time was highly statistically significantly different (p < 0.01) between the groups in terms of education, and these results increased with the higher level of education. The total time spent on sitting together with travel time was also highly statistically significant different (p < 0.01) between the groups, and these results increased with the higher level of education. The time spent watching TV was highly statistically significantly different (p < 0.01), varied depending on education, and these results decreased with the higher level of education (Table 3).
The time spent in the sitting position on days off differed highly significantly (p < 0.01) depending on the BMI, and the lowest results referred to a group of people with standard BMI. The time spent watching television was highly significant different (p < 0.01) depending on the BMI, and these results increased with increasing BMI (Table 4).
The relationship between the amount of time spent sitting and various diseases (diabetes, hypertension, coronary artery disease, heart failure, stroke, asthma, COPD, cancer) was also analyzed (Table 5).
In the case of time spent in a sitting position at weekends depending on the occurrence of diabetes, the difference was significant (p < 0.05) and higher scores were related to people with diabetes. The time spent watching TV was highly significantly (p < 0.01) among people with diabetes (Table 6).
In the case of the time spent in the sitting position depending on the occurrence of hypertension, the difference was significant (p < 0.05) and higher results were related to people with hypertension. The time spent watching TV was highly significantly (p < 0.01) in patients with hypertension (Table 7).
In the case of coronary artery disease, the amount of time spent in a sitting position on days off proved highly significant (p < 0.01), and higher results were reported in people with such a disease. Also, time spent watching TV was significantly higher (p < 0.05) among patients with coronary artery disease (Table 8).
The time spent sitting on weekdays, the total and average sitting time and the sitting time including travel time differed highly significantly (p < 0.01) depending on the occurrence of heart failure, and higher results were reported in people who did not suffer from the disease (Table 9).
The results of the scales of time spent sitting did not differ significantly (p > 0.05) depending on the occurrence of stroke and asthma (Table 10 and 11).
The results of the scales of time spent sitting did not differ significantly (p > 0.05) depending on the occurrence of COPD, except for the time spent watching television, where the difference was highly significant (p < 0.01), and more time watching television was spent by people with COPD than those without the condition (Table 12).
The time spent sitting on weekdays differed highly significantly (p < 0.01) depending on the occurrence of cancer, and higher results were reported in people without the disease. In the case of time spent in a sitting position at weekends, the difference was not significant (p > 0.05). The total and average sitting time differed highly significantly (p < 0.01) between groups, and higher results were reported in the group free from the disease. The total sitting time including travel time differed highly significantly (p < 0.01) depending on the occurrence of cancer, and higher results were reported in people without the disease. The time spent watching TV was not significantly different (p > 0.05) between the groups (Table 13).
In the case of the time spent in the sitting position at weekends depending on the number of diseases, the difference was highly significant (p < 0.01), and the results increased with the higher number of the diseases. Also, the time spent watching television was highly significantly different (p < 0.01) depending on the number of diseases, and the results increased with the higher number of diseases (Table 14).

Discussion

In the last ten years, the behavior associated with a sedentary lifestyle has emerged as a new risk factor influencing health. Behaviors associated with sedentary lifestyles are characterized by forms of activity such as walking, which requires the energy expenditure at the level of 1.0 to 1.5 of the basal metabolism, sitting or resting.
Typical behaviors associated with sedentary lifestyles include watching television, using the computer, and the time spent sitting. Epidemiological studies carried out on different age groups show that a significant number of waking hours (without sleep) is spent on sitting, which poses new challenges to public health [4].
Our results showed that with the increase of the level of education, the amount of time spent sitting on weekdays increases, while the amount of time spent watching television decreases. With the increase of the level of education, the amount of total and average sitting time, including travel time also increases. The relationship between a sedentary lifestyle and education and other features is confirmed by Proper, who in his study of 1,048 adult Australians from areas of different socio-economic status showed that gender, age, socio-economic status, education, working time, and physical activity are associated with sitting time during weekdays, at weekends, and in spare time [5].
Our findings also evaluated the relationship between the amount of time spent sitting and BMI, and this relationship turned out to be highly significant. The time spent in the sitting position in spare time differed highly significantly (p < 0.01) depending on the BMI, and the lowest rates referred to a group of people with a standard BMI. Also, the time spent watching television was highly significantly different (p < 0.01) depending on the BMI, and these results increased with increasing BMI.
The above results were confirmed by the study conducted by Gennuso, who showed that more time spent on the behavior associated with a sedentary lifestyle was associated with higher BMI (p < 0.01) [6].
Similarly, in a study conducted by Stamatakis, free time spent on a sitting activity reported by study participants ( 0.088; 95% CI: 0.047–0.130) was associated with BMI [7].
Gomez-Cabello, in turn, showed that sitting for more than four hours a day increased the risk of overweight (OR 1.7; 95% CI: 1.06–2.82) and obesity (OR 2.7; 95% CI: 1.62–4.66). In a similar study, Gomez-Cabello showed that sitting for more than four hours per day increased the risk of overweight/obesity (OR 1.42; 95% CI: 1.06–1.89) and excess fat (OR 1.4; 95% CI: 1.14–1.74) in women and risk of central obesity (OR 1.74; 95% CI: 1.21–2.49) in men [8].
Stamatakis also showed that the time spent watching television (0.159; 95% CI: 0.0104–0.215) was positively associated with BMI [7].
In the study, which assessed the sedentary behavior in transport, Frank showed that ≥ 1 hour a day sitting in the car was not associated with overweight (OR 0.86; 95% CI: 0.51–1.22) or obesity (OR 0.67; 95% CI: 0.41–1.06) [9].
Bullock in the study of 5,338 people from the UK, the USA, Germany, Spain, Italy, France, Portugal, Austria, and Switzerland rated BMI, total physical activity (MET-minutes/week), and sitting time (hours/day). Participants were grouped into quartiles based on their daily sitting time (< 4, 4 – ≤ 6, 6 – ≤ 8, and > 8 hours/day). Studies have shown that the participants in the highest sitting time quartile (≥ 8 hours/day) had 62% higher chances for obesity compared to participants in the lowest quartile (< 4 hours/day), after adjustment for physical activity and other confounding variables (OR 1.62; 95% CI: 1.24–2.12, p < 0.01). The author showed that the sitting time is associated with obesity, independent of physical activity [10].
In our study, we evaluated WHR and WC indexes, which indicated that standard WHR was reported in 30% of participants and abdominal obesity in 70% of cases. Standard WC was observed only in 29% of cases. The relation between abdominal obesity and a sedentary lifestyle was not analyzed. However, Gardiner and Gomez-Cabello showed that the time spent sitting increased the risk of abdominal obe¬sity by 80% (OR 1.8; 95% CI: 1.20–2.70) in both sexes and by 81% in women (OR 1.8; 95% CI: 1.21–2.70) [8, 11].
Gennuso showed that longer time spent sitting was associated with a large waist circumference (p = 0.01). In the population of people who overcame colorectal cancer, the time spent on sitting behavior was not associated with waist circumference [6].
In the study conducted by Stamatakis, the time spent watching television ( 0.416; 95% CI: 0.275–0.558) and overall free time spent on the activity related with a sedentary lifestyle ( 0.234; 95% CI: 0.129–0.339) was positively associated with waist circumference [7].
Similarly, Gao showed that longer time spent on watching television was associated with high WHR (3.9; 95% CI: 1.08–8.4; p = 0.01) [12].
The authors of the present study have also attempt to assess the relationship between sedentary lifestyles and the prevalence of diseases. Our findings analyzing the relation between the amount of time spent sitting with diabetes, have shown that in the case of the time spent in a sitting position at weekends, the difference is significant (p < 0.05), and higher scores are reported in people with diabetes. Also, the time spent watching TV was highly significantly higher (p < 0.01) among people with diabetes. However, it is not known whether sitting is a factor of exposure or the result of a disease because the study design for such an assessment does not allow for this type of assessment.
The observations made in patients with type 2 diabetes, which evaluated the relationship between physical activity related to the job performed, commuting to work and free time, and overall mortality and cardiovascular causes are also interesting. The study involved 3,316 patients with type 2 diabetes aged 25–74. Three levels of physical activity at work were distinguished: light physical activity – a simple physical work and sitting (e.g. office work), moderate physical activity – walking and standing (e.g. work of a shop assistant), and active physical activity – walking and moving heavy objects (e.g. working as a warehouseman). In the period of 18 years, 64% of deaths among patients were due to cardiac causes. After considering a number of parameters (age, sex, year of study, BMI, systolic blood pressure, cholesterol, smoking, and types of physical activity), which underwent modifications during the observation, it was showed that the participants actively spending their free time reported 30% lower risk of death, and those moderately active, 15% lower risk compared with those who preferred a sedentary lifestyle. It was also observed that not only physical activity in leisure time, but also physical activity related to the job performed and commuting prevented deaths from cardiac causes in patients with type 2 diabetes. The results of the study showed that in patients with type 2 diabetes who walk a lot and carry various items during physical work, the risk of death from cardiac causes is lower by 40%. Diabetic patients actively using their free time and following a proper diet can prevent the development of type 2 diabetes or delay it [13–16].
According to Sienkiewicz, aerobic exercise and strength training also allow for better glycemic control and reduce mortality in patients with type 2 dia¬betes, particularly in the sub-group of people with the highest risk of the disease [13].
In our study, we also evaluated the relationship between sedentary lifestyles and the occurrence of cardiovascular disease – hypertension, coronary artery disease, and heart failure. In the case of hypertension and coronary heart disease, the differences were highly significant and sitting time was higher in the group of people with the discussed diseases. Such relations were not observed in the case of heart failure. The patients in the study suffered from these diseases. There are also numerous publications confirming the importance of physical activity as a risk factor for cardiovascular disease.
Over 50 years ago, a pioneering work of Morris was published, which outlines the hypothesis concerning the relation between low physical activity and coronary heart disease (CHD) among London bus drivers. It was also documented that physical inactivity is a major risk factor for CHD in the Western population [13].
Barengo after studying 15,853 men and 16,824 women aged 30-59 living in Eastern and Southwestern Finland, showed that a sedentary lifestyle, which is the minimum level of activity both at work and at play, is associated with a statistically significant increase in the incidence of cardiovascular disease (CVD) and overall mortality among men and women. Cardiovascular disease and overall mortality were observed less frequently in people who were moderately or very physically active in their leisure time, compared with those leading a sedentary lifestyle. Also, moderate and high levels of occupational physical activity reduced the risk of CVD and mortality by 21–27% in both sexes. In women, walking at least 15 minutes a day or riding a bicycle to and from work, lower the incidence level of cardiovascular disease and reduced overall mortality. Therefore, the promotion of even a moderate level of physical activity in leisure time and at work, may play an important role in the prevention of premature CVD and overall mortality. The protective effect of physical activity on overall mortality was similar to the effect on mortality related to CVD, which may indicate that moderate and high levels of physical activity also protect patients from causes other than cardiovascular disease [17].
Ogum and Shinoda-Tagawa conducted a meta-analysis of 30 studies on the effects of physical activity on the occurrence of CVD in women. Based on the review of the research, covering a period of 37 years, the relationship between physical activity in women initially healthy and the incidence of CVD, especially CHD and stroke, was determined. Physical activity was associated with a reduction in the occurrence of cardiovascular disease in women. The results showed that physically inactive women would benefit even if they increased their physical activity only slightly (e.g. walking 1 hour a week or even less) and even greater benefits could be observed with the increase of physical activity [18].
Rastogi, assuming that the level of physical activity for people from urban areas in India is now comparable to that of the West, conducted a study to assess the relation between physical activity and the risk of CHD. The authors observed a positive correlation between the lack of activity outside work and the risk of CHD. Following a multivariate analysis, it was observed that people who spent more than 3.6 hours per day on “sitting activity” (e.g. watching television) compared with people spending less than 70 minutes a day, the risk level has increased to 1.88 (95% CI: 1.09–3.20). Exercises performed during leisure time (equivalent to 35–40 minutes a day of brisk walk) protected against the development of CHD, while sedentary lifestyle positively correlated with the risk of coronary heart disease [19].
Protective effects of physical activity in different parts of the World were also demonstrated in a study INTER HEART. It was observed that a regular physical activity was significantly associated with a reduction in the incidence of acute myocardial infarction, independent of other risk factors [20]. According to Richardson’s observation that individuals with high-risk of CVD benefit greatly from an active lifestyle [21].
Our findings regarding the amount of time spent on sitting did not differ significantly depending on the occurrence of stroke. The question is why the appearance of the disease, which often leads to patient’s immobilization in bed and dependence on third parties, was not a motivating factor for the study participants to follow a more active lifestyle.
In a meta-analysis carried out by Wendel-Vos, which included a total of 31 publications, physical activity of medium intensity, compared with the absence of activity, protected participants against stroke both in the case of professional activity (RR = 0.64; 95% CI: 0.87–0.48] and leisure time activity (RR = 0.85; 95% CI: 0.78–0.93). High levels of physical activity protect against ischemic stroke, both in comparison with moderate activity levels (RR = 0.77; 95% CI: 0.60–0.98) and its absence at work (RR = 0.57; 95% CI: 0.43–0.77). The results of research conducted in Europe showed a stronger protective effect of physical effort (RR = 0.47; 95% CI: 0.33–0.66) than the results of observations conducted in the United States (RR = 0.82; 95% CI: 0.75–0.90). The lack of physical activity, however, was a modifiable risk factor for both the total stroke incidents and their subtypes [22]. In other meta-analyzes it was confirmed that the lack of physical activity was also an important risk factor for stroke. In some published studies, the protective effect of physical activity on stroke remains controversial [13].
The last analyzed group of diseases were cancers (malignant neoplasm). In this case, the results concerning the relationship between the amount of time spent sitting and the above group of diseases were different from other groups. The study participants reported that the amount of time spent sitting on weekdays, the total, average sitting time, and the sitting time including travel time was significantly lower in relation to people with no such diseases. The data may indicate that cancer, which results in significant fear, is a factor that encourages patients to follow a more active lifestyle. It is also possible that these changes are related to medical advice.
The literature review conducted by Lynch, 18 arti¬cles related to behaviors associated with a sedentary lifestyle and cancer risk or behaviors associated with a sedentary lifestyle and health outcomes in cancer survivors were identified. Ten of these studies showed a statistically significant positive relationship between behavior related to a sedentary lifestyle and cancers. The behavior associated with a sedentary lifestyle was associated with an increased risk of developing colorectal cancer, endometrial cancer, ovarian cancer, and prostate cancer, increased mortality due to cancer in women, and weight gain in colon cancer survivors. A review of the literature on the behavior of sedentary lifestyles supported the hypothetical role of obesity and metabolic disorders, as causative mechanisms in the relationship between the behavior associated with a sedentary lifestyle and cancer [23].
According to Lee and Thune, physical activity of moderate intensity (> 4.5 MET) performed by 30–60 minutes a day is associated also with a lower incidence of some cancers, especially colorectal cancer (in men and women 30–40% lower) and breast cancer (in women 20–30% lower), in comparison with morbidity in patients whose physical activity is smaller [24, 25].
Tuchowska, in turn, states that abnormal body weight may increase the risk of colon and breast cancer, and regular exercises can significantly reduce the incidence of colon cancer. Physical activity also reduces the risk of breast cancer and endometrial cancer in women, and in men with prostate cancer [26].
In our study, we also highlighted the relationship between sedentary lifestyle and the number of occurring diseases. It seems that a sedentary lifestyle has a connection with the number of diseases, but to date, there has been no literature, to which any reference could be made. These relationships are particularly evident in relation to time spent sitting at weekends and watching TV.
Numerous scientific studies on sitting lifestyle pay attention to its relationship to mortality risk.
The study conducted by Martinez-Gomez showed that people who spent less than 8 hours a day sitting, showed a lower risk of all-cause mortality (HR = 0.70; 95% CI: 0.60–0.82) compared with those in the same age, but following a sedentary lifestyle. Moreover, physically active people who do not follow a sedentary lifestyle (less than 8 hours a day sitting), showed a lower risk of all-cause mortality (HR 0.44; 95% CI: 0.36–0.52) than those physically inactive and leading a sedentary lifestyle [27].
Similarly, Pavey observed that people who spent 8 to 11 hours a day sitting (HR 1.52; 95% CI: 1.17–1.98), showed a higher risk of all-cause mortality than those who spent fewer than 8 hours a day sitting. With every hour spent sitting, the all-cause mortality risk increased by 3% (HR 1.03; 95% CI: 1.01–1.05). Furthermore, the risk of all-cause mortality in patients who were not physically active (less than 150 minutes of activity per week) and spent from 8 to 11 hours or over 11 hours a day sitting, increased by 31% (HR 1.31; 95% CI: 1.07–1.61) and 47% (HR 1.47; 95% CI: 1.15–1.93) [28].
By studying a population of people who overcame colorectal cancer, Campbell pointed out that more than 6 hours per day of leisure time spent sitting prior to the diagnosis, compared with less than 3 hours per day, were associated with a higher risk of all-cause mortality (RR 1.36; 95% CI: 1.10–1.68) and a mortality resulting from other causes (not cardiovascular and not associated with colorectal cancer) (RR 1.48; 95% CI: 1.05–2.08). The time spent sitting after the diagnosis (colon cancer) (> 6 hours) was associated with a higher risk of all-cause mortality (RR 1.27; 95% CI: 0.99–1.64), and mortality resulting directly from colorectal cancer (RR 1.62; 95% CI: 1.07–2.44) [29].
The results of the study by Warburton et al. who observed that in the patients with multiple risk factors, but who are at the same time regular exercisers, the likelihood of premature mortality is lower than in patients without risk factors who lead a sedentary life. Regular exercise can reduce total mortality by more than 50%. The influence of physical activity on mortality was observed not only in the primary, but also for the secondary prevention of cardiovascular diseases [30].
The results of the presented studies revealed the extent of the problem of sedentary lifestyle and its health consequences. In view of the fact that in most societies a sedentary lifestyle begins to dominate, priority should be given to the introduction of recommendations regarding the implementation of regular physical activity from childhood to old age.

Conclusions

1. Men prefer a sedentary lifestyle more often than women.
2. With the increase in the level of education, the amount of time spent sitting on weekdays, the total and average sitting time, and the total sitting time including travel time increases, while the amount of time spent on watching television decreases.
3. Sedentary lifestyle is related with the values of body mass index. The study participants with a normal body mass index spend less time sitting on days off work, compared to overweight and obese people. With the increase in BMI, the amount of time spent on watching TV increases.
4. Cardiovascular diseases, respiratory diseases, and diabetes are associated with a sedentary lifestyle. The amount of time spent sitting in people who suffer from these diseases is higher than in those without these diseases. Reverse dependencies are reported in the case of cancer, which for many patients may actually determine a lifestyle change.
5. Multiple morbidities lead to the increased amount of time spent sitting, and these relationships are particularly evident in relation to the time spent sitting on the days off and watching TV.
6. There is a need to implement prevention programs that promote physical activity among the residents of Kielce.

Conflict of interest

The authors declare no conflict of interest.

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Address for correspondence:

Małgorzata Biskup
Zakład Rehabilitacji
Świętokrzyskie Centrum Onkologii
3 Artwińskiego St.
25-734 Kielce
Phone: +48 606 645 865