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eISSN: 2719-3209
ISSN: 0023-2157
Klinika Oczna / Acta Ophthalmologica Polonica
Bieżący numer Archiwum Filmy Artykuły w druku O czasopiśmie Suplementy Rada naukowa Recenzenci Bazy indeksacyjne Prenumerata Kontakt Zasady publikacji prac Opłaty publikacyjne Standardy etyczne i procedury
Panel Redakcyjny
Zgłaszanie i recenzowanie prac online
SCImago Journal & Country Rank
3/2009
vol. 111
 
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Artykuł oryginalny

Zastosowanie optycznej koherentnej tomografii w monitorowaniu leczenia zwyrodnienia plamki związanego z wiekiem metodą terapii fotodynamicznej

Jarosław Piłat
1
,
Edward Wylęgała
1, 2

  1. Oddział Okulistyki Okręgowego Szpitala Kolejowego, Samodzielny Publiczny Zakład Opieki Zdrowotnej w Katowicach
  2. Zakład Pielęgniarstwa i Społecznych Problemów Medycznych Śląskiego Uniwersytetu Medycznego w Katowicach
Klinika Oczna 2009, 111 (3): 229-234
Data publikacji online: 2009/10/14
Pełna treść artykułu Pobierz cytowanie
 
Wstęp
Of our study is to check usefulness of OCT exam in qualification for PDT, and as independent diagnostic tool. OCT exam gives quantification of parameters for monitoring PDT. Correlation between the results of OCT exams and visual acuity was estimated as well as the prognosis of PDT efficacy on the basis of results from OCT exams.

Materiał i metody
59 eyes of 56 patients with CNV caused by AMD were examined and treated PDT. OCT and BCVA examination were done before PDT, 1 week, 4 weeks and 12 weeks after PDT. OCT measurement: minimal retinal thickness in fovea, average retinal thickness in fovea, retinal volume in fovea and total retinal volume in macula. STRATUS OCT 3000 with soft. v.4.0.2 (0056) was used. All 59 eyes form group D. The eyes were divided into two antagonist subgroup: D1 – 38 eyes with visual acuity stabilization or worsening and D2 – 21 eyes with visual acuity improvement 12 weeks after PDT.

Wyniki
There was correlation between results in exams of retinal thickness and volume in macula. Group D has significant decrease of minimal retinal thickness, average retinal thickness in fovea and retinal volume in fovea 4 weeks after PDT. In subgroup D1 there was statistically significant decrease of minimal retinal thickness and total retinal volume in macula, 12 weeks after PDT. There was in subgroup D1 positive correlation between relative changes of total retinal volume in macula and relative changes of BCVA four weeks after PDT.

Wnioski
OCT exam is very useful in qualification for PDT, but it could not be an independent diagnostic tool. Useful quantification of parameters in OCT exam are retinal thickness and retinal volume. OCT does not allow to prognosis efficacy of PDT.



Introduction
Of our study is to check usefulness of OCT exam in qualification for PDT, and as independent diagnostic tool. OCT exam gives quantification of parameters for monitoring PDT. Correlation between the results of OCT exams and visual acuity was estimated as well as the prognosis of PDT efficacy on the basis of results from OCT exams.

Material and methods
59 eyes of 56 patients with CNV caused by AMD were examined and treated PDT. OCT and BCVA examination were done before PDT, 1 week, 4 weeks and 12 weeks after PDT. OCT measurement: minimal retinal thickness in fovea, average retinal thickness in fovea, retinal volume in fovea and total retinal volume in macula. STRATUS OCT 3000 with soft. v.4.0.2 (0056) was used. All 59 eyes form group D. The eyes were divided into two antagonist subgroup: D1 – 38 eyes with visual acuity stabilization or worsening and D2 – 21 eyes with visual acuity improvement 12 weeks after PDT.

Results
There was correlation between results in exams of retinal thickness and volume in macula. Group D has significant decrease of minimal retinal thickness, average retinal thickness in fovea and retinal volume in fovea 4 weeks after PDT. In subgroup D1 there was statistically significant decrease of minimal retinal thickness and total retinal volume in macula, 12 weeks after PDT. There was in subgroup D1 positive correlation between relative changes of total retinal volume in macula and relative changes of BCVA four weeks after PDT.

Conclusions
OCT exam is very useful in qualification for PDT, but it could not be an independent diagnostic tool. Useful quantification of parameters in OCT exam are retinal thickness and retinal volume. OCT does not allow to prognosis efficacy of PDT.

słowa kluczowe:

optyczna koherentna tomografia, grubość siatkówki, objętość siatkówki, terapia fotodynamiczna, centralna neowaskularyzacja, zwyrodnienie plamki związane z wiekiem

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