Acanthosis nigricans – częsta choroba, niezwiązana na ogół z procesami złośliwymi

Robert A. Schwartz; Edmund J. Janniger

eISSN: 2084-9893
ISSN: 0033-2526

Dermatology Review/Przegląd Dermatologiczny

Current issue Archive Manuscripts accepted About the journal Special Issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

1/2011
vol. 98

Send email

Copy url:

abstract:

Special paper

Acanthosis nigricans – częsta choroba, niezwiązana na ogół z procesami złośliwymi

Robert A. Schwartz

,

Edmund J. Janniger

Przegl Dermatol 2011, 98, 1–6

Online publish date: 2011/03/04

View full text Get citation

Acanthosis nigricans (AN) can be a highly significant cutaneous finding and is usually unrelated to cancer. It is most often evident as velvety thickening of axillae, posterior neck fold, flexor skin surfaces and umbilicus. It is common in obesity, which is seen increasing in children and adolescents, and can serve as a cutaneous marker of insulin resistance. It is most often associated with hyperinsulinemia, which may result from insulin receptor gene defects causing insulin resistance, and less frequently due to mutations in fibroblast growth factor receptors. In this work non malignancy-associated AN types will be emphasized, particularly the association of AN with insulin-resistance, itself a potential threat to life.

keywords:

Acanthosis nigricans – częsta choroba, niezwiązana na ogół z procesami złośliwymi

Robert A. Schwartz , Edmund J. Janniger

acanthosis nigricans, obesity, insulin resistance, fibroblast growth factor receptors, insulin receptors, drug eruptions

Robert A. Schwartz

,

Edmund J. Janniger