Allergen immunotherapy in patients with autoimmune diseases: current of guidelines and emerging controversies

Dominika Ochab-Krupnik; Adam Latos; Piotr Łacwik; Maciej Kupczyk; Cezary Pałczyński

doi:10.5114/pja.2024.145211

eISSN: 2391-6052
ISSN: 2353-3854

Alergologia Polska - Polish Journal of Allergology

Current issue Archive Manuscripts accepted About the journal Supplements Special issues Editorial board Abstracting and indexing Subscription Contact Instructions for authors Publication charge Ethical standards and procedures

Editorial System

Submit your Manuscript

Editorial Policies

Sarajevo Declaration on Integrity and Visibility of Scholarly Publications

Open access

Send email

Copy url:

abstract:

Review paper

Allergen immunotherapy in patients with autoimmune diseases: current of guidelines and emerging controversies

Dominika Ochab-Krupnik

^{1, 2}

,

Adam Latos

³

,

Piotr Łacwik

^{1, 2}

,

Maciej Kupczyk

⁴

,

Cezary Pałczyński

^{1, 2}

Collegium Medicum, Jan Kochanowski University, Kielce, Poland
Clinical Division of Lung Diseases and Allergology, Holy Cross Centre for Lung Disease, Chęciny, Poland
ESCULAP Medical and Dental Clinic, Puławy, Poland
Department of Internal Medicine, Asthma and Allergy, Medical University of Lodz, Poland

Alergologia Polska – Polish Journal of Allergology

DOI: https://doi.org/10.5114/pja.2024.145211

Online publish date: 2024/11/21

View full text Get citation

PlumX metrics:

This review examines the use of allergen immunotherapy (AIT) in patients with comorbid autoimmune diseases, addressing ongoing controversies and gaps in current clinical guidelines. The purpose of this article is to explore the complex relationship between allergic and autoimmune diseases and to determine the safety of AIT in this patient population. Historical case reports and recent observational studies were reviewed, highlighting cases in which AIT has been associated with exacerbations of autoimmune diseases. However, these reports often involved older, less purified allergen extracts, raising questions about their relevance to current practice. The review also assessed international guidelines, revealing inconsistencies and a reliance on outdated evidence. The findings suggest the need for more rigorous, large-scale studies to provide clear guidelines for the safe use of AIT in patients with autoimmune diseases. This review underscores the need for updating clinical practices to align with contemporary evidence, ensuring that AIT is applied safely and effectively in patients with autoimmune conditions.

keywords:

Allergen immunotherapy in patients with autoimmune diseases: current of guidelines and emerging controversies

Dominika Ochab-Krupnik 1, 2 , Adam Latos 3 , Piotr Łacwik 1, 2 , Maciej Kupczyk 4 , Cezary Pałczyński 1, 2

allergen immunotherapy, autoimmune diseases, immunotherapy contraindications

Dominika Ochab-Krupnik

^{1, 2}

,

Adam Latos

³

,

Piotr Łacwik

^{1, 2}

,

Maciej Kupczyk

⁴

,

Cezary Pałczyński

^{1, 2}