eISSN: 1897-4252
ISSN: 1731-5530
Kardiochirurgia i Torakochirurgia Polska/Polish Journal of Thoracic and Cardiovascular Surgery
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2/2006
vol. 3
 
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abstract:

Anestezjologia i intensywna terapia
Coronary artery bypass grafting in abciximab: treated non-elective patients

Rafał Drwiła
,
Marcin Ziętkiewicz
,
Dariusz Plitzner
,
Bogusław Kapelak
,
Krzysztof Wróbel
,
Paweł Moncznik
,
Maria Śnieżek-Maciejewska
,
Jerzy Sadowski
,
Janusz Andres

Kardiochir Torakochir Pol 2006; 3, 2: 187-193
Online publish date: 2006/08/31
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Background: Between January 2002 and September 2005 abciximab was used in 1150 patients with a wide spectrum of cardiological interventions in our haemodynamic department. Among them 48 were operated on for cardiopulmonary bypass (CPB). 12 were operated on in non-elective mode not later than 14 days after abciximab use. Material and methods: The group of 12 patients operated on in non-elective mode during which the potential effect of abciximab was compared with the group of 80 coronary patients operated on also non-electively. Both groups received heparin and aspirin during the preoperative period. We analyzed postoperative drainage and use of blood and blood products. Results: Blood loss and transfusions of packed red cells and fresh frozen plasma were similar in both groups. The volume of transfused platelets was higher in the abciximab-treated group (p<0.01). Conclusions: Risk of post-operative bleeding is similar in non-elective patients receiving heparin/aspirin after abciximab compared to the group treated with heparin/aspirin alone. There is still no gold-standard test for platelet function assessment available.
keywords:

cardiopulmonary bypass, abciximab
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