Case report <br>Adult sublingual schwannoma with angioma-like features and foam cell vascular change

Sarah Taconet; Philippe Gorphe; Adriana Handra-Luca

doi:10.5114/fn.2014.45571

eISSN: 1509-572x
ISSN: 1641-4640

Folia Neuropathologica

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3/2014
vol. 52

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abstract:

Case report
Adult sublingual schwannoma with angioma-like features and foam cell vascular change

Sarah Taconet

,

Philippe Gorphe

,

Adriana Handra-Luca

Folia Neuropathol 2014; 52 (3): 298-302

DOI: https://doi.org/10.5114/fn.2014.45571

Online publish date: 2014/09/26

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Schwannomas are benign, slow-growing neoplasms of the neural sheaths. They occur rarely in a sublingual location; 9 cases have been reported to our knowledge. We aimed to report the case of a sublingual schwannoma with peculiar morphological features. A 23-year-old woman presented for a right sublingual mass, clinically diagnosed as a vascular malformation. A pleomorphic adenoma was suggested by cytology examination. The diagnosis of schwannoma was made on the resected specimen. The tumour, measuring 4.1 cm, showed several angioma-like vessel agglomerates and macrophage thickening of the intratumour vessel wall. Tumour cells expressed diffusely S100 protein, as well as CD56 and podoplanin. In conclusion, we report the case of a sublingual schwannoma, of peculiar morphology, with presence of pseudo-angioma aggregates and foam cell thickening of the vessel wall, features which were of clinical relevance.

keywords:

Case report Adult sublingual schwannoma with angioma-like features and foam cell vascular change

Sarah Taconet , Philippe Gorphe , Adriana Handra-Luca

schwannoma, salivary gland, sublingual, differential diagnosis, angioma, macrophage, podoplanin/D240, NCAM/CD56, CD68

Case report
Adult sublingual schwannoma with angioma-like features and foam cell vascular change

Sarah Taconet

,

Philippe Gorphe

,

Adriana Handra-Luca